Obesity Clinical Trial
Official title:
Differences in Physiological Responses of Satiety and Reward After (in)Consistent Calorie Cues.
The regulation of our food intake is on the short-term guided by appetite and satiety
signals generated by the sight and consumption of food. Food intake is not only regulated by
appetite and satiety signals - external cues also play an important role.
It has been observed that food intake and the pleasure derived from consumption is affected
by manipulation of the external cues.
The investigators will assess the contribution of food anticipation (calorie information)
and actual consumption of a test food (calorie intake) on in satiety responses (such as
ghrelin responses, appetite and subsequent food intake). The investigators expect the
information on the amount of calories, rather than the actual amount of calories in the
food, to predict the ghrelin responses and the subsequent intake of a second meal.
In a randomized cross-over design with 4 conditions, all participants will consume twice the low-caloric food (once with the low-calorie information and once with the high-calorie information) and twice the high-caloric food (again, once with the low-calorie information and once with the high-calorie information) in a randomized order. ;
Allocation: Randomized, Intervention Model: Crossover Assignment, Masking: Single Blind (Subject), Primary Purpose: Basic Science
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