Obesity Clinical Trial
Official title:
Acute Effects of Zantrex-3 on Energy Expenditure and Appetite Sensations
Background: Zantrex-3® is a popular dietary supplement for weight control, which consists of
a combination of yerba mate, guarana, caffeine and damiana. The combination has previously
been shown to decrease gastric emptying and its weight controlling effects may be related to
increased satiety and thermogenesis.
Objective: To investigate the effect of Zantrex-3® on energy expenditure, hemodynamic
factors and subjective appetite sensations.
Design: Twenty-three men (BMI: 23.9±3.2 kg/m2, mean±SD) participated in a randomized,
double-blind, placebo-controlled crossover study. The Zantrex-3® compound contained 365 mg
xantines (caffeine and caffeine-like stimulants), yerba mate, guarana and damiana. The
thermogenic effect was measured for 3 hours post-intake. Blood pressure (BP), heart rate
(HR) and appetite ratings were assessed every half hour.
n/a
Allocation: Randomized, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Prevention
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