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Brain Activation in Response to Appetitive Cues Pre- and Post- Bariatric Surgery

Obesity Clinical Trial

Official title:
Brain Activation in Response to Appetite Cues Pre- and Post- Bariatric Surgery

Clinical Trial Summary

Utilizing fMRI, this study will examine changes in BOLD signal as a proxy measure of brain activation in response to highly palatable (high energy density [kcal/g]), less palatable and non-food stimuli in severely obese women pre, 1 month post and 3 months post undergoing bariatric surgery (in surgery patients) and at equivalent times for control groups in fed and fasted conditions at each time point.

Two surgical groups: (i) laparoscopic Roux-en-Y gastric bypass (RYGB) and (ii) gastric banding (GB) will be compared with two control groups: (i)those enrolled on a 3-month formula weight loss program or (ii) those who qualify, but do not undergo bariatric surgery, and receive no weight loss treatment.

Clinical Trial Description

n/a

Study Design

Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Open Label, Primary Purpose: Basic Science

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01590914
Study type Interventional
Source New York Obesity and Nutrition Research Center
Contact
Status Enrolling by invitation
Phase N/A
Start date January 2008
View Details
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