Effects of Time of Sleep Restriction in Obesity

Obesity Clinical Trial

Official title: Effect os Sleep Restriction on Control of Food Intake and Metabolism of Obese Subjects

Status Completed

Clinical Trial Summary

The purpose of this study is to determine the effect of different time of sleep restriction on control of food intake and metabolism of obese and normal subjects.

Clinical Trial Description

The reduction of sleep time has now become a common habit, driven by the demands and opportunities of modern society. Some studies have suggested that sleep restriction would be an important factor in predisposing to obesity. However studies of sleep restriction in obese individuals have not yet been conducted. Still, the time of sleep restriction varies greatly between studies, making it difficult to compare results.

The investigators aim to recruit 20 young adults, 10 obese and 10 normal weight individuals. The study will be conducted as a randomized, crossover study with three conditions. Each participant will be subjected to reduction of the beginning of sleep (from 3-7h), reduction of the end of sleep (from 23-3h), and normal sleep (from 23-7h), in random order, for three consecutive nights.

In each condition, subjects will stay for 4 days in the laboratory. Three control meals will be offered. Visual analogue scales will be applied before and after each meal to assess hunger and appetite for different food categories. Blood samples will be collected hourly during 24 hours. ;

Study Design

Observational Model: Case-Crossover, Time Perspective: Cross-Sectional

Related Conditions & MeSH terms

• Appetite Regulation
• Eating
• Obesity
• Sleep Restriction

• NCT number: NCT01259895
• Study type: Observational
• Source: Federal University of São Paulo
• Status: Completed
• Phase: N/A
• Start date: February 2009
• Completion date: June 2012