Obesity Clinical Trial
Official title:
Migraine, Appetite Behaviour and Obesity: is There a Link?. A Pilot Study of Migraine and Appetite Behaviour in Children.
The purpose of this study is to determine whether there is an association between migraine in children and certain patterns of appetite or eating behaviour that may lead to later obesity.
Migraine is a chronic neurological disorder characterized by recurrent episodes of headache
and associated symptoms. The condition affects approximately 11% of the child population and
it can impose considerable burdens on the sufferer either due to the headache itself, or
associated co-morbidities such as psychological stress, obesity, sleep problems, etc.
Increasing attention is focussing on the shared genetic, environmental and neurobiological
mechanisms of migraine co-morbidities to gain further insights into improving outcomes.
We are interested in studying eating behaviours in children with migraine since there is
evidence that altered patterns of eating behaviour (and underlying changes in appetite) are
seen in migraineurs although not studied systematically. Altered appetite and eating
behaviours may be a mechanism for the emerging association between obesity (or degree of
adiposity) and migraine severity, detected in both adult and paediatric studies to varying
extents. Studying the putative association between migraine, degree of adiposity and
patterns of eating behaviour in children may help to tease out causal mechanisms, since both
migraine and obesity often evolve over the course of childhood.
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Observational Model: Case-Only, Time Perspective: Cross-Sectional
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