Obesity Clinical Trial
Official title:
Sleep Apnea Syndrome in Obese Women During Pregnancy
Excess weight or obesity is associated with an increased risk of health disorders: high blood
pressure, diabetes, cardiovascular risks, dyslipidemia and sleep apneas. During pregnancy in
obese women, the risk of preeclampsia increases by three and the risk of fetal death in utero
by five. Snoring and Obstructive sleep apnea (OSA) may be associated with increased risk of
adverse pregnancy outcomes, including maternal cardio pulmonary status, fetal heart rate and
fetal acidosis-basis status by recurrent upper-airway obstruction, hypoventilation, and
intermittent nocturnal hypoxia. Reports in pregnancy have identified in association with OSA
and preeclampsia, intrauterine growth restriction and stillbirth.
The prevalence of OSA among women is estimated to be 2-5%, but it remains underdiagnosed
during pregnancy. In sleep apnea syndrome, a few data have shown better pregnancy and fetal
outcome with the use continuous positive airway pressure (CPAP) therapy.
the hypothesis is in obese pregnant women that there could be a significant association
between sleep apnea syndrome and hypertensive disorders, preeclampsia and adverse fetal
outcomes This is a prospective study of Women with a body mass index of 35 kg.m2 or greater.
The aim of this study is to determinate the prevalence of sleep apnea syndrome in obese
pregnant women and the benefit of CPAP on the maternal and fetal outcome.
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