The Effect of Whey Protein on Short-Term Food Intake and Post-Meal Blood Glucose Response in Young Men

Obesity Prevention Clinical Trial

Official title:

The Effect of Whey Protein on Short-term Food Intake and Post-meal Blood Glucose Response in Young Men

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00988377
• Other study ID #: Kraft_whey protein: study 1
• Status: Completed
• Phase: N/A
• First received: September 30, 2009
• Last updated: October 1, 2009
• Start date: May 2007
• Est. completion date: November 2007

Study information

• Verified date: October 2009
• Source: University of Toronto
• Contact: n/a
• Is FDA regulated: No
• Health authority: Canada: Ethics Review Committee
• Study type: Interventional

Clinical Trial Summary

The objective of this study was to describe relationships among whey protein when consumed before a meal on food intake and pre- and post-meal satiety, blood glucose in healthy young adults.

Description:

A randomized, cross-over design study was conducted. Whey protein preloads (10-40 g) were provided in 300 ml water. At 30 min following consumption, subjects were fed an ad libitum pizza meal. Satiety, and blood glucose were measured at baseline and selected intervals pre- (0, 15 and 30 min) and post-meal (50, 65, 80 and 95 min).

Recruitment information / eligibility

• Status: Completed
• Enrollment: 16
• Est. completion date: November 2007
• Est. primary completion date: August 2007
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Male
• Age group: 20 Years to 27 Years

Eligibility

Inclusion Criteria:

• healthy

• normal weight ( 18-24.9 kg/m²)

• young aged 20-27 year old

Exclusion Criteria:

• breakfast skippers

• smokers

• dieters

• individuals with diabetes (fasting BG = 7.0 mmol/L) or other metabolic diseases

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Single Blind (Subject), Primary Purpose: Prevention

Related Conditions & MeSH terms

• Diabetes Prevention
• Obesity Prevention

Intervention

Other:
• dietary intervention
whey protein 10-40 g
• water control
Iso-volumetric (300 ml) water control (Crystal Springs, Canada)

Locations

Country	Name	City	State
Canada	University of Toronto, Department of Nutritional Sciences	Toronto	Ontario

Sponsors (3)

Lead Sponsor	Collaborator
University of Toronto	Mondelez International, Inc., Natural Sciences and Engineering Research Council, Canada

Country where clinical trial is conducted

Canada, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Blood glucose subjective appetite Food intake at 30 min		0-95 min	No
Secondary	physical comfort palatability		0-95 min	No