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Clinical Trial Summary

To assess the potential usefulness of radiogenomics for tumor driving genes heterogeneity in non-small cell lung cancer.


Clinical Trial Description

Patients with advanced NSCLC underwent 18F-FDG PET/CT and PET/CT-guided synchronous targeted biopsy of primary and distant metastatic tumors. The LIFEx package was used to extract PET and CT radiomic features from primary and metastatic lesions. The radiomic ROI sites of primary and distant metastatic tumors were point-to-point corresponding to the PET/ CT-guided targeted biopsy sites. Whole exon sequencing of primary and distant metastatic tumor samples obtained by PET/CT-guided targeted biopsy was used to get genomic data of primary and distant metastatic tumor. Predictive radiogenomics models were established and validation. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04553601
Study type Interventional
Source The First Affiliated Hospital of Xiamen University
Contact Long Sun, PhD
Phone 86 0592-2137077
Email 13178352662@163.com
Status Recruiting
Phase N/A
Start date October 1, 2019
Completion date October 1, 2022

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