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Impact of Sex and Age on Non-visual Light Input That Affects Sleep and Circadian Rhythms

Normal Physiology Clinical Trial

Official title:
Impact of Sex and Age on Non-visual Light Input That Affects Sleep and Circadian Rhythms

Clinical Trial Summary

The goal of this clinical trial is to learn how the pupil responds to different light stimuli and how that relates to sleep and daily rhythms in healthy people of different ages. The main questions it aims to answer are: - Does the eye's pupil response to light stimuli differ by the sex and age of the participant? - Is the eye's pupil response to light stimuli related to each participant's sleep timing, their body clock timing, and their hormone responses to light. Participants will have a special eye exam and complete questionnaires before starting the study to see if they can participate. If they can participate, they will wear a special watch that monitors their activity and light levels for one week. Then they will live in a research room at the Mass General Hospital for 3 days/2 nights during which we will test their pupil response to light, their body clock timing, and their hormone responses to light.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05829044
Study type Interventional
Source Massachusetts General Hospital
Contact Elizabeth B Klerman, MD PhD
Phone 617-643-2424
Email ebklerman@mgh.harvard.edu
Status Recruiting
Phase N/A
Start date December 1, 2023
Completion date December 2026
View Details
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