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Vitamin E Dosing Study — VEDS  

Nonalcoholic Steatohepatitis Clinical Trial

Official title:
Vitamin E Dosing Study (VEDS): A Dose Finding Study of Vitamin E for the Treatment of Adult NAFLD

Clinical Trial Summary

This is a multicenter, randomized, double masked, placebo-controlled, parallel treatment groups dosing trial of Vitamin E in adult nonalcoholic fatty liver disease (NAFLD).

Clinical Trial Description

Adults age 18 years or older will be enrolled for 48 weeks and treated with 200 international units (IU), 400 IU, or 800 IU of Vitamin E or matching placebo for 24 weeks. The primary objective of the study is to determine the minimum effective dose of Vitamin E (d-alpha-tocopherol) based upon relative change in alanine aminotransferase (ALT) from baseline to 24 weeks. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04801849
Study type Interventional
Source National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Contact Emily Mitchell, MS, MBA
Phone 410-955-8183
Email esharke5@jhu.edu
Status Recruiting
Phase Phase 2
Start date August 5, 2022
Completion date August 30, 2025
View Details
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