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Clinical Trial Summary

This study will assess the safety and efficacy of avutometinib (VS-6766) monotherapy or VS-6766 in combination with defactinib in subjects with recurrent Non-small cell lung cancer.


Clinical Trial Description

This is a multicenter, open-label Phase 2 study designed to evaluate safety and tolerability and efficacy of avutometinib (VS-6766) versus avutometinib (VS-6766) in combination with defactinib in subjects with KRAS and BRAF mutant NSCLC following treatment with an appropriate platinum-based regimen and an approved immune checkpoint inhibitor (CPI). ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04620330
Study type Interventional
Source Verastem, Inc.
Contact
Status Completed
Phase Phase 2
Start date December 31, 2020
Completion date December 12, 2023

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