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K-RAS and EGFR in Lung Cancer — K-RAS_NSCLC  

Non Small Cell Lung Cancer Clinical Trial

Official title:
Genotyping K-RAS and EGFR in Greek Non-small-cell Lung Cancer Patients: Incidence, Significance and Treatment Implications

Clinical Trial Summary

Retrospective analysis where patients with histologically confirmed Non-small cell lung cancer (NSCLC) were centrally evaluated for the presence of KRAS and EGFR mutations.

Clinical Trial Description

A retrospective analysis, performed by the Hellenic Co-operative Oncology Group (HeCOG), in samples from patients with histologically confirmed NSCLC, who had been treated within HeCOG-affiliated centres from March 2000 through December 2012, were centrally evaluated for the presence of KRAS and EGFR mutations. All patients had available clinicopathological data at diagnosis. Formalin-fixed, paraffin-embedded tissue blocks were retrospectively retrieved from the HeCOG tumor repository. Cytologic material was prospectively submitted for genotyping in more recent years (2010-2012). ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03951233
Study type Observational
Source Hellenic Cooperative Oncology Group
Contact
Status Completed
Phase
Start date March 2000
Completion date December 2014
View Details
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