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Clinical Trial Summary

The purpose of this study is to evaluate the efficacy of icotinib in combination with radiotherapy for NSCLC patients with brain metastases. The primary endpoint is PFS of intracranial lesions


Clinical Trial Description

Non-small cell lung cancer (NSCLC) is one of the malignant tumors with the highest incidence of brain metastases. Patients with brain metastasis showed poor prognosis and displayed an untreated median survival of only 3-6 months, and most patients died due to the progression of brain metastases. Some research showed that Icotinib alone can improve the efficiency of NSCLC with brain metastases, but there is still unknow about the result about combination with EGFR-TKI and radiotherapy. This study is designed to evaluate the efficacy of icotinib combined with radiotherapy for NSCLC patients with brain metastases. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03754530
Study type Interventional
Source Betta Pharmaceuticals Co.,Ltd.
Contact Li jiancheng
Phone 86+13906900190
Email jianchengli6@126.com
Status Not yet recruiting
Phase Phase 2
Start date December 1, 2018
Completion date December 1, 2021

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