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Non-Small Cell Lung Cancer clinical trials

View clinical trials related to Non-Small Cell Lung Cancer.

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NCT ID: NCT03209128 Terminated - Clinical trials for Non Small Cell Lung Cancer

Cerebral Prophylactic Irradiation With Saving Hippocampus and Amygdala

IPC
Start date: April 20, 2017
Phase:
Study type: Observational

Hippocampus and amygdala are parts of the brain involved in the recognition of emotions, memories, memory, language ... It is therefore very important to protect them during irradiation of the brain. The aim of this study is to evaluate cerebral irradiation with saving hippocampus and amygdala protects these brain functions in patients with small cell lung cancer (SCLC) Radiotherapy of the brain

NCT ID: NCT03202940 Active, not recruiting - Clinical trials for Non-small Cell Lung Cancer

A Phase IB/II Study of Alectinib Combined With Cobimetinib in Advanced ALK-Rearranged (ALK+) NSCLC

Start date: September 14, 2017
Phase: Phase 1/Phase 2
Study type: Interventional

This research study is studying a drug combination as a possible treatment for anaplastic lymphoma kinase-positive (ALK+) non-small cell lung cancer. The drugs involved in this study are: - Alectinib - Cobimetinib

NCT ID: NCT03201146 Recruiting - Lung Cancer Clinical Trials

Apatinib Combine With Platinum‐Based Doublet Chemotherapy for First-line Treatment of Advanced NSCLC

Start date: June 27, 2017
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to evaluate the safety and clinical activity of Apatinib in combination with AP(Pemetrexed/Carboplatin) or AC(Pemetrexed/Carboplatin) as first-line chemotherapy in subjects with advanced EGFR wild type non-squamous non-small cell lung cancer(NSCLC).

NCT ID: NCT03199599 Completed - Clinical trials for Non Small Cell Lung Cancer

Prognostic PET/CT Model in Non Small Cell Lung Cancer

Start date: September 1, 2016
Phase:
Study type: Observational

Prospective validation of a prognostic model based on advanced PET/CT image analysis in non small cell lung cancer

NCT ID: NCT03198923 Recruiting - Clinical trials for Non-small Cell Lung Cancer

Clinical Efficacy and Safety of NK and NKT Cells Infusion in Patients With Non Small Cell Lung Cancer

Start date: September 13, 2017
Phase: Phase 1
Study type: Interventional

The purpose of this study is to assess the safety and effectiveness of natural killer (NK) cell and natural killer T (NKT) cell-based immunotherapy in subjects with non small cell lung cancer.

NCT ID: NCT03198468 Completed - Lung Cancer Clinical Trials

Vapor Ablation for Localized Cancer Lesions of the Lung (VAPORIZE)

VAPORIZE
Start date: November 21, 2018
Phase: N/A
Study type: Interventional

This study is a prospective, single-arm, multi-center, pilot trial of Bronchoscopic Thermal Vapor Ablation for Lung Cancer (BTVA-C) in patients with primary lung cancer or metastatic cancer in the lung. Patients who have consented to participate in this study (enrolled) will be subject to eligibility screening and baseline assessments, prior to undergoing the BTVA-C procedure. Only patients that meet all of inclusion criteria and none of the exclusion criteria will receive vapor ablation treatment. Patients will receive BTVA-C treatment followed by standard-of-practice surgical resection.

NCT ID: NCT03198117 Terminated - Clinical trials for Non-small Cell Lung Cancer

Huaier Granule for Prevention of Recurrence and Metastasis of Stage II and III Non-small Cell Lung Cancer (NSCLC)

Start date: April 25, 2017
Phase: N/A
Study type: Interventional

This study including two parts,one part is a randomized clinical trial design,another part is a registration study.

NCT ID: NCT03196986 Completed - Clinical trials for Non-small Cell Lung Cancer

mil60 Versus Bevacizumab in Patients With Treatment-naïve Non-squamous Non-small Cell Lung Cancer

Start date: August 15, 2017
Phase: Phase 3
Study type: Interventional

This randomized, double-blind, multi-center phase 3 study is aimed to compare the efficacy and safety of mil60 with bevacizumab as first-line treatment when combined with standard chemotherapy (paclitaxel/carboplatin) in treatment-naive patients with advanced or recurrent non-squamous NSCLC.

NCT ID: NCT03195699 Active, not recruiting - Breast Cancer Clinical Trials

Oral STAT3 Inhibitor, TTI-101, in Patients With Advanced Cancers

Start date: November 15, 2017
Phase: Phase 1
Study type: Interventional

Many patients have cancers that have increased activity of a protein called STAT3 that contributes critically to the development and growth of their cancer. Despite our knowledge of STAT3's importance to cancer, scientists and doctors have not developed a drug that targets it and that patients can take to treat their cancer more effectively than treatments that are now available. Tvardi Therapeutics, Incorporated has developed a compound, TTI-101, which can be given by mouth and acts as a direct inhibitor of STAT3. Administration of TTI-101 to mice demonstrated that it blocked growth of cancers of the breast, head and neck, lung, and liver and it was safe when administered at high doses to mice, rats, and dogs. In this application, Tvardi is proposing to further develop TTI-101 for treatment of solid tumors for which the prognosis is dismal. The investigators will determine how safe it is when administered to patients with cancer, determine whether an adequate dose can be administered to patients with cancer that will block STAT3 in their cancer, and determine whether treatment with TTI-101 leads to reduced growth of their cancer.

NCT ID: NCT03195569 Recruiting - Clinical trials for Non Small Cell Lung Cancer

To Predict Efficacy by Detecting Circulating Endothelial Cell Subsets and Blood Perfusion Parameters Changes in Vivo Tumor in Study of QL1101 and Avastin® in Patients With Non-squamous Non-small Cell Lung Cancer

Start date: March 1, 2017
Phase: N/A
Study type: Observational [Patient Registry]

To reveal changes of peripheral markers and blood perfusion parameters in vivo tumor in the study of QL1101 and Avastin® in patients with Non-squamous Non-small Cell Lung Cancer