Nocturnal Polyuria Clinical Trial
Official title:
Watershift - Pilot Study: Observing the Interindividual Effects and Mechanims of the Uptake, Storage and Excretion of Water
The aim of this pilot was to study how body water behaves between the different internal
water pools of the human body, what the role and influence of the interstitium is and what
the effect is of body position on the distribution and allocation of BW between different
body parts (trunk, legs, arms). To study this, 2 techniques that have not been used before in
urological research were tested on their usefulness:
- The first technique is a recent BIA device, which distinguishes itself from earlier
devices by measuring impedance at different electrical currencies in different body
parts (arm/limb/trunk). This technique made it possible to observe the influence of body
position on the distribution of BW in these body compartments. Rationale for this
research question is mainly the link between NP and edema that was found in earlier
research and the fact that body position seemed to have an impact on the size of edema.
For this reason, it can be suggested that body position and thus edema will have an
impact on whether or not NP occurs.
- The second technique uses deuterium as a biological marker. With this technique the
distribution, storage, allocation and excretion of BW was examined among the urological
most relevant water pools (blood, urine and interstitium).
n/a
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