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Clinical Trial Summary

This study assesses if using the medication desmopressin will decrease nightime bedwetting in children with sickle cell disease.


Clinical Trial Description

Night time bedwetting is a common complication of sickle cell disease, and affects up to 30 % of children. Desmopressin is an oral medication that increases water reabsorption in the kidneys. Studies have shown that it is effective in decreasing bedwetting episodes in children without sickle cell disease. Chronic sickling episodes causing damage to the kidneys could cause permanent damage and may make this treatment ineffective in sickle cell disease. This trial will inform pediatric sickle cell doctors if desmopressin is an appropriate treatment for bed wetting in the investigators patients. This study expanded upon a previously terminated study which had separately registered (NCT02636387, ID: 2014-3768). ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04420585
Study type Interventional
Source Montefiore Medical Center
Contact
Status Terminated
Phase Phase 4
Start date July 7, 2020
Completion date June 12, 2023

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