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Nociceptive Pain clinical trials

View clinical trials related to Nociceptive Pain.

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NCT ID: NCT03556137 Recruiting - Neuropathic Pain Clinical Trials

PET/MRI in the Diagnosis of Chronic Pain

Start date: July 16, 2018
Phase: Phase 1
Study type: Interventional

Several studies have implicated involvement of sigma-1 receptors (SR1s) in the generation of chronic pain, while others are investigating anti SR1 drugs for treatment of chronic pain. Using [18F]-FTC-146 and positron emission tomography/magnetic resonance imaging (PET/MRI), the investigators hope to identify the source of pain generation in patients with chronic pain. The purpose of this study is to compare the uptake of [18F]FTC-146 in healthy volunteers to that of individuals suffering from chronic pain.

NCT ID: NCT03498898 Recruiting - Nociceptive Pain Clinical Trials

The Effect of Ongoing Beta-blockers Administration on Analgesic Requirements in the Immediate Perioperative Period.

Start date: June 1, 2018
Phase: N/A
Study type: Interventional

This study is designed to discover if chronic use of Beta adrenergic receptor blockers affects pain sensation during and after an elective procedure of hip or knee replacement. The study's population will be divided to four groups: Group A- chronic use of Beta adrenergic receptor blockers undergoing total hip replacement, Group B- no use of Beta adrenergic receptor blockers undergoing total hip replacement, Group C- chronic use of Beta adrenergic receptor blockers undergoing total knee replacement and Group D- no use of Beta adrenergic receptor blockers undergoing total knee replacement. Each patient will be anesthetized using the same anesthesia protocol with pain assessment done by the ANI device intra operatively and by NRS score postoperatively.

NCT ID: NCT03422783 Recruiting - Anesthesia Clinical Trials

Correlation Between NOL Index After Stimulus and Post-operative Opioid, Pain, Pre-operative Phenotype

Start date: January 15, 2018
Phase: N/A
Study type: Interventional

This study evaluates the correlation between NoL index response to standardized stimulus under general anesthesia and the post-operative pain, assessed by opioid consumption and numerical pain scores after video-assisted thoracoscopy (VATS).

NCT ID: NCT00945919 Recruiting - Neuropathic Pain Clinical Trials

A Pilot Study of Ultra Rapid Opioid Rotation and Titration of Oxymorphone

Start date: July 2009
Phase: N/A
Study type: Interventional

This project will explore the safety and feasibility of performing a successful intravenous patient controlled analgesia (IV PCA) Oxymorphone titration and conversion to oral ER Oxymorphone (extended release or OPANA ER) in the outpatient setting.