Colonoscopy Using Nitrous Oxide- A Pilot Study in the USA

Nitrous Oxide Clinical Trial

Official title: Colonoscopy Using Nitrous Oxide- A Pilot Study in the USA

Status Completed

Clinical Trial Summary

Colon cancer is the second most common cancer in men and the third most common cancer in women worldwide. The clinical objectives of administering sedation for GI endoscopy are to relieve patient anxiety and discomfort and to improve the outcome of the examination. Use of N2O could potentially provide an alternate safe and cheap option for patients who do not prefer IV sedation for colonoscopy

Clinical Trial Description

Patients who are considered low risk for anesthesia administration (ASA class <IV) receive moderate sedation with a combination of intravenous benzodiazepine and opioid medication. an alternative method of providing analgesia with "on-demand" inhalation of nitrous oxide (hereafter referred to as N2O) combined with oxygen has been postulated. Nitrous Oxide has been used for analgesia in various procedures including childbirth, general anesthesia, pediatric dentistry, bone marrow aspiration, fracture reductions, and minor surgical procedures (surgical dressings, pulmonary endoscopy, an abscess . It could potentially reduce overall costs for the procedure, in addition to providing a quicker recovery, turn over ;

Related Conditions & MeSH terms

• Nitrous Oxide

• NCT number: NCT04305158
• Study type: Interventional
• Source: University of Arkansas
• Status: Completed
• Phase: Early Phase 1
• Start date: March 28, 2022
• Completion date: August 10, 2023