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Newborn; Infection clinical trials

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NCT ID: NCT06389383 Active, not recruiting - Newborn; Infection Clinical Trials

Pilot Study - Monitoring the Nasal Microbiome and Viral Respiratory Infections in Newborn Hospitalized in Neonatalogy.

NEONATMICROBIO
Start date: December 21, 2022
Phase: N/A
Study type: Interventional

The objective of our study is therefore to study the evolution of the respiratory microbiome of hospitalized newborns, its interaction with viral infections and their impacts on the evolution of newborns.

NCT ID: NCT05226949 Completed - Neonatal Sepsis Clinical Trials

Host RNA Expression Profiles and Protein Biomarkers in Neonatal Herpes Simplex Virus Infection

Start date: January 1, 2022
Phase:
Study type: Observational

This study seeks to identify and test host RNA expression profiles in context to protein biomarkers in dried blood spot samples as novel diagnostic markers of neonatal herpes simplex virus infection and to improve the understanding of the pathogenesis of the disease.

NCT ID: NCT05175027 Completed - Circumcision Clinical Trials

Preoperative Antiseptic in Newborn Circumcision Comparison of Povidone Iodine and Hypochlorous Acid Used

Start date: May 5, 2021
Phase: N/A
Study type: Interventional

Comparison of Povidone iodine and Hypochlorous acid used as a Preoperative Antiseptic in Newborn Circumcision abstract Aim: Circumcision is one of the most common surgical procedures in all age groups. Before the circumcision procedure, asepsis is provided with a surface disinfectant. Various methods can be used for this process. Povidone iodine, which has been used for years during the transition from traditional circumcision methods to surgical circumcision methods; tissue damage, allergic reactions and increase in pain level. For this reason, the investigators aimed to compare it with Hypochlorous acid (Crystalin), which is a less toxic and more physiological antiseptic solution. Material and Method: Newborns to be circumcised randomly were divided into two groups as Hypochlorosis group and Povidone iodine group. At the beginning of the circumcision procedure, a culture was taken in the form of a prepucial swab 1 minute after the cleaning of the local area and the inner surface of the prepuce. Then circumcision was performed. Culture results and complications were compared.

NCT ID: NCT04862403 Completed - Newborn; Infection Clinical Trials

The Effect of Umbilical Cord Clamping Distance

Start date: June 1, 2018
Phase: N/A
Study type: Interventional

A randomized control trial was conducted to test the effect of umbilical cord clamping distance on cord separation time and umbilical cord microbial colonization in neonates.

NCT ID: NCT03688607 Not yet recruiting - Newborn; Infection Clinical Trials

Deploying POKE Within Intermountain Healthcare

POKE
Start date: October 1, 2018
Phase:
Study type: Observational

To assess the impact of POKE on babies, the investigators will longitudinally track outcomes before and after implementation at Intermountain Healthcare's five NICUs. Process outcomes will include the number of total POKEs per baby and the number of painful POKEs per baby, each measured at both the patient-level and NICU-level. Clinical outcomes will include hospital acquired infections, length of stay, and mortality. Financial outcomes will include total variable costs and backfill rate. The effect of POKE on each of these outcomes will be measured using multivariable regression analysis with appropriate distributional families and interaction terms.

NCT ID: NCT03282292 Withdrawn - Clinical trials for Congenital Heart Disease

Central Venous Catheter Insertion Site and Colonization in Pediatric Cardiac Surgery

PRECiSE
Start date: September 12, 2017
Phase: N/A
Study type: Interventional

Randomized controlled trial comparing femoral vs internal jugular insertion site of central venous catheters (CVC) in newborns and infants undergoing cardiac surgery. The experimental hypothesis is that the jugular insertion site is superior to the femoral in terms of catheter colonization.

NCT ID: NCT03183531 Completed - Newborn; Infection Clinical Trials

New Protocol for Febrile Neonate Management

Start date: January 1, 2011
Phase: N/A
Study type: Observational

The objective of present study was to evaluate clinical and laboratory characteristics of febrile neonate and describe the incidence of SBI in febrile neonates. Secondarly investigators aimed to test usefulness of major protocols and new protocol in evaluating only febrile neonate.