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Nevus, Pigmented clinical trials

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NCT ID: NCT06206681 Recruiting - Keratosis Clinical Trials

Efficacy and Safety of Ultrapulse Carbon Dioxide Laser Treatment in Eyelid Tumors

Start date: November 1, 2022
Phase:
Study type: Observational

This study aims to assess the long-term efficacy and safety of ultrapulse carbon dioxide (CO₂) laser excision in the treatment of eyelid tumors, including xanthelasma, pigmented nevi, keratoses, and so on.

NCT ID: NCT05402046 Recruiting - Melanoma (Skin) Clinical Trials

Clinical vAlidation of a MobilE appLication ("ProRodinki") in the Assessment of the maLignant skIn neoplAsms

CAMELLIA
Start date: April 23, 2022
Phase: N/A
Study type: Interventional

A Multicenter, Prospective, Low-interventional Clinical Study Evaluating on mobile application validation ("ProRodinki") in assessing the risk of skin malignant neoplasms

NCT ID: NCT04548817 Recruiting - Clinical trials for Large Cutaneous Melanocytic Nevi

Neurocutaneous Melanocytosis Registry

Start date: September 3, 2020
Phase:
Study type: Observational [Patient Registry]

This study will involve collecting information about the regular medical care you receive for large cutaneous melanocytic nevi (LCMN) or neurocutaneous melanocytosis (NCM).

NCT ID: NCT04353050 Recruiting - Melanoma Clinical Trials

Atypical MOLes and Melanoma Early Detection Study (MoleMed)

MoleMed
Start date: April 1, 2020
Phase: N/A
Study type: Interventional

This is a multicenter, ambispective, low-interventional clinical study evaluating molecular genetic markers for non-invasive differential diagnosis of benign and malignant pigmented skin and mucosal neoplasms. In retrospective cohorts genetics markers will be identified. In prospective cohort non-invasive adhesive system will be tested to identify malignant or benign lesions with prespecified sensitivity and specificity compared to other non-invasive techniques (i.e. dermoscopy) and using histopathological examination as a "golden standard".

NCT ID: NCT03699995 Recruiting - Cutaneous Melanoma Clinical Trials

MoleMapper, Visiomed, and Confocal Microscopy in Screening Participants for Melanoma

Start date: May 18, 2018
Phase: N/A
Study type: Interventional

This trial studies how well MoleMapper, Visiomed, and confocal microscopy work in screening participants for melanoma. Analyzing images (photographs) made with three different portable imaging systems may be as good as a visit to a dermatologist's office for finding melanomas before they can spread.

NCT ID: NCT03054584 Recruiting - Melanocytic Nevi Clinical Trials

Genetic Basis of Melanocytic Nevi

Start date: June 26, 2017
Phase:
Study type: Observational

The objective of this protocol is to further elucidate the genetic mutations that drive melanocytic nevi (benign melanocytic neoplasms, moles). This will be performed by whole genome, whole exome, or targeted sequencing of de-identified specimens. Herein, the investigators plan to isolate DNA from de-identified skin biopsy specimens and blood samples: 1. From melanocytic nevi collected by skin biopsy (a shave or punch biopsy). A part of the tissue will be submitted for routine diagnostic dermatopathology and investigational histomorphologic and immunohistochemical analysis. 2. From corresponding normal tissue (blood). DNA isolated from blood will be used as a normal control when analyzing sequencing data to identify somatic mutations in lesional tissue.

NCT ID: NCT02280889 Recruiting - Quality of Life Clinical Trials

Quality of Life and Stigmatization in Children With Congenital Melanocytic Nevi Before and After Nevus Excision

Start date: May 2013
Phase:
Study type: Observational

Congenital melanocytic nevi (CMN) are a quite common congenital disorder. Over years, surgical excision was proposed to the patients because transformation into a malignant skin tumor (melanoma) was feared. Recent data proof that the risk for malignancy was overestimated. Nowadays still a lot of patients express their wish for surgical removal out of aesthetic reasons and psychological impacts. Many patients and families experience stigmatization because of the nevus. To proof a medical indication for surgical removal the investigators want to evaluate the quality of life and stigmatization before and after nevus surgery.