Neuropathic Pain Clinical Trial
Official title:
Cannabinoids Effects on the Pain Modulation System
Effective treatment of acute pain, chronic and persistent is the most important concern in
the world today. Although a variety of pain medications including anti-inflammatory
painkillers and opiouids, patients continue to suffer from pain constantly. For over a
century ,International committees studied the issue of cannabis, and almost uniformly
recommended the use of cannabis for various medical applications ,especially those that
include pain treatment.
Despite the widespread use of THC in clinical practice, there are few studies on the efficacy
of THC In a double-blind, randomized trial. In addition, few studies examined the effect of
THC on the experience pain in healthy subjects and most of them did not find an effect on
pain experimental induced by capsain. so checking other models of pain such as thermal pain
and mechanical pain in addition to checking the influence on the regulation of pain will
contribute to understanding the mechanism of action of THC. Understanding the mechanism of
action of THC in relieving pain will lead to predicting who will benefit from this treatment
and direct patients for selection of appropriate medication according to the damaged
mechanism.
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