Continuous Adductor Canal Block for Total Knee Arthroplasty Analgesia

Neuromuscular Blockade Clinical Trial

Official title:

Prospective Comparison Between Continuous Femoral Nerve Block and the Association of Adductor Canal Block and Sciatic Nerve Block in Total Knee Arthroplasty.

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT02387021
• Other study ID #: P-2015002/AR
• Status: Not yet recruiting
• Phase: N/A
• First received: March 4, 2015
• Last updated: March 7, 2015
• Start date: March 2015
• Est. completion date: December 2015

Study information

• Verified date: March 2015
• Source: Institut Kassab d'Orthopédie
• Contact: Karim Raies, M.D
• Phone: +21655208602
• Email: karim.raies[@]gmail.com
• Is FDA regulated: No
• Health authority: Tunisia: Ministry of Public Health
• Study type: Interventional

Clinical Trial Summary

The purpose of the study is to determine whether the association of sciatic nerve block to continuous adductor canal block is effective in the treatment of total knee arthroplasty post operative pain .

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 80
• Est. completion date: December 2015
• Est. primary completion date: December 2015
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 18 Years to 90 Years

Eligibility

Inclusion Criteria:

• Elective unilateral TKA,

• Planned continuous spinal anesthesia ,

• Ability to follow study protocol,

• American Society of Anesthesiologists class 1 to 3.

Exclusion Criteria:

• Contraindication for neuraxial anesthetic,

• Chronic opioid use (defined as daily or almost daily use of opioids for >3 months),

• Hypersensitivity and/or allergies to any of the study medications,

• Intraoperative use of volatile anesthetics,

• Preexisting neuropathy on the operative limb,

• Contraindications to a femoral, adductor canal or Tibial nerve block.

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

• Neuromuscular Blockade
• Pain Management

Intervention

Procedure:
• Continuous femoral nerve block

• Continuous adductor canal block

• infragluteal Sciatic nerve block

Drug:
• Ropivacaine 0.2%

• Saline

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Institut Kassab d'Orthopédie

References & Publications (1)

Kim DH, Lin Y, Goytizolo EA, Kahn RL, Maalouf DB, Manohar A, Patt ML, Goon AK, Lee YY, Ma Y, Yadeau JT. Adductor canal block versus femoral nerve block for total knee arthroplasty: a prospective, randomized, controlled trial. Anesthesiology. 2014 Mar;120(3):540-50. doi: 10.1097/ALN.0000000000000119. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Total Opioid-consumption	Cumulative opioid consumption : converting oral, intravenous, and patient-controlled analgesia PCA opioid to morphine equivalent	8 hours postoperative	No
Secondary	NRS pain score at rest	NRS pain scores determined by patient interview, using the standard NRS of 0 to 10 scale at rest.	0,1,2,4,6,8,12,24 and 48 hours postoperative	No
Secondary	NRS pain score during movement	NRS pain scores determined by patient interview, using the standard NRS of 0 to 10 scale, during physiotherapy.	0,1,2,4,6,8,12,24 and 48 hours postoperative	No
Secondary	NRS pain score after 10 meters of walk or maximum walked distance	NRS pain scores determined by patient interview, using the standard NRS of 0 to 10 scale after 10 meters walk (if enable after maximum walked distance).	8, 24 and 48 hours postoperative	No
Secondary	Ability to walk	The ability of the patient to stand up and walk 3 meters.	8, 24 and 48 hours postoperative	No
Secondary	TUG Test	The TUG test measures the time it takes a patient to stand up from a chair, walk a distance of 3 m, and return to the chair	8, 24 and 48 hours postoperative	No
Secondary	The 10-m walk test	time it takes the patient to walk a distance of 10 m as quickly as possible	8, 24 and 48 hours postoperative	No
Secondary	patient satisfaction	patient interviewed, using a scale of 0-10, 0 not satisfied and 10 being the most satisfied	8, 24 and 48 hours postoperative	No