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Clinical Trial Summary

This study aims to compare total intravenous anesthetic agents: combined remimazolam and propofol vs. propofol monotherapy. The comparison parameters are intraoperative hypotension, patient's involuntary movement, neurophysiological monitoring quality, onset time, recovery time, and postoperative rescue anti-emetics requirements.


Clinical Trial Description

This study hypothesizes that the combination regimen of remimazolam and propofol as total intravenous anesthesia in neurosurgical procedures requiring neurophysiological monitoring can reduce the incidence of hypotension compared to propofol monotherapy while providing comparable levels of neurophysiological monitoring and surgical conditions. With this hypothesis, the study aims to compare the frequency, severity, and duration of hypotension, frequency of patient movement, and appropriateness of neurophysiological monitoring between the combination therapy of remimazolam and propofol and propofol monotherapy in total intravenous anesthesia. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT06382467
Study type Interventional
Source Chung-Ang University Gwangmyeong Hospital
Contact Jiwon Han, Pf.
Phone 821034471988
Email yesuroon@gmail.com
Status Not yet recruiting
Phase Phase 4
Start date May 2024
Completion date June 2025

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