Neuroendocrine Tumors Clinical Trial
Official title:
Studio Esplorativo Monocentrico Non Controllato, in Aperto, Volto a Sviluppare e Valutare l'Applicazione di Una Tecnica Innovativa di Rimozione Radioguidata Dei Tumori Neuroendocrini Gastro-entero-pancreatici
Radioguided surgery (RGS) with beta- radioisotopes is a novel approach focused on developing
a new probe which, detecting electrons and operating with low background, provides a clearer
delineation of the margins of lesions with low radiation exposition for surgeons.
To validate this procedure, ex vivo specimens of tumours expressing somatostatin receptors,
as small-intestine neuroendocrine (SI-NET), will be tested
Small Intestinal neuroendocrine patients, with a positive Ga-68-DOTATOC PET/CT, will receive
a small amount of beta- radiopharmaceutical (Y-90-DOTATOC), and then operated, as clinical
indicated.
Tissue samples will be tested ex-vivo with a beta-probe prototype
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