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Neuroendocrine Tumors clinical trials

View clinical trials related to Neuroendocrine Tumors.

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NCT ID: NCT04129255 Completed - Clinical trials for Neuroendocrine Tumors

Octreotide LAR in the Induction of Immunologic Response in NENs Patients

CSMS99
Start date: June 28, 2017
Phase: Phase 2
Study type: Interventional

Evaluating the impact of OCTREOTIDE LAR on the immune response by studying Regulatory T-cell (T-Reg) and Myeloid-derived suppressor cells (MDSC) and the immunoregulatory cell population in peripheral blood of NET G1 / G2 patients treated with Octreotide LAR

NCT ID: NCT03967951 Completed - Clinical trials for Pancreatic Neuroendocrine Tumor

CT Radiomic Features of Pancreatic Neuroendocrine Neoplasms

Start date: March 23, 2019
Phase:
Study type: Observational

The aim of this study is to quantify inter-observer variability in delineating pancreatic neuroendocrine neoplasm (PanNEN) on Computerized Tomography (CT) images and its impact on radiomic features (RF), subsequently to this determination, to use CT texture analysis to predict, histological characteristics of PanNEN on CT scans.

NCT ID: NCT03948841 Completed - Clinical trials for Neuroendocrine Tumors

Measurement Variability of Liver Metastases From Neuroendocrine Tumors on Different Magnetic Resonance Imaging Sequences

NETMRI
Start date: January 1, 2011
Phase:
Study type: Observational

The aim of our study is to assess variability of measurements of liver metastases from neuroendocrine tumors (NET) on different magnetic resonance imaging (MRI) sequences. In this institutional review board-approved retrospective study from January 2011 to December 2012, all liver MRIs performed at our department in patients with proven liver metastases from NETs and with at least one measurable lesion according to Response evaluation criteria in solid tumors (RECIST 1.1) were included.

NCT ID: NCT03883776 Completed - Clinical trials for Neuroendocrine Tumors

Al18F-NOTA-octreotide PET Imaging of the Somatostatin Receptor in Neuroendocrine Tumors

Start date: April 11, 2019
Phase: Phase 1
Study type: Interventional

The aim of this study is to evaluate the potential of Al18F-1,4,7-triazacyclononane-1,4,7-triacetate-octreotide (Al18F-NOTA-octreotide) as a positron emission tomography (PET) somatostatin receptor imaging agent in patients with neuroendocrine tumors.

NCT ID: NCT03873870 Completed - Clinical trials for Neuroendocrine Tumors

68Ga-DOTATATE PET for Management of Neuroendocrine Tumors

Start date: March 28, 2019
Phase: N/A
Study type: Interventional

This is a research study to collect information regarding usefulness of positron emission tomography (PET) scans using a special dye called 68Ga-DOTATATE for patients with neuroendocrine tumours by determining the number of of patients whose clinical management was changed as a result of the scans.

NCT ID: NCT03870399 Completed - Clinical trials for Neuroendocrine Tumors

Study of Tamoxifen in Well Differentiated Neuroendocrine Tumors and Hormone Receptor Positive Expression

HORMONET
Start date: March 13, 2019
Phase: Phase 2
Study type: Interventional

This is a single-arm, unicentric, single-stage clinical study of tamoxifen for patients with well differentiated neuroendocrine tumors and radiological progression with positive (> 1 percent) HR (estrogen and / or progesterone) expression by IHC. It will evaluate if Tamoxifen exerts antitumor action in patients with well differentiated NET and positive for the expression of HR, estrogen and / or progesterone.

NCT ID: NCT03852693 Completed - Clinical trials for Neuroendocrine Tumors of the Appendix

Distant Metastases and Long-Term Survival After Complete Resection of Neuroendocrine Tumors of the Appendix

SurvivApp
Start date: October 1, 2020
Phase:
Study type: Observational [Patient Registry]

The aim of the present project is to evaluate the frequency of distant metastases and clinically relevant relapse and mortality, respectively, of aNEN (Neuroendocrine Neoplasms of the Appendix) measuring 1 - 2 cm. The investigators hypothesize that the mortality rate of aNET (Neuroendocrine Tumors of the Appendix) measuring 1 - 2cm is less than 1%. Furthermore, the investigators hypothesize that regional lymph node metastases of aNET measuring 1 - 2 cm are clinically not relevant and are not associated with reduced survival. The investigators therefore hypothesize that oncological right-sided hemicolectomy has no impact on long-term survival after complete resection of aNET measuring 1 - 2 cm and that the malignant potential quo ad vitam of these tumors is lower than the risk of oncological hemicolectomy.

NCT ID: NCT03840720 Completed - Clinical trials for Neuroendocrine Tumors

The Patient's Journey - the Time to Final Diagnosis in Patients With SiNET

Start date: February 1, 2019
Phase:
Study type: Observational

"The patient's journey" is an interview based study assessing the patients' experience from the first symptoms to a final diagnosis focusing on patients with small intestinal neuroendocrine tumors.

NCT ID: NCT03834701 Completed - Clinical trials for Neuroendocrine Tumors

Endoscopic Ultrasound-guided RadioFrequency Ablation for the Treatment Pancreatic NeuroEndocrine Neoplasms

RAPNEN
Start date: September 1, 2019
Phase: N/A
Study type: Interventional

This study evaluates the possibility and the safety of performing local therapy for Pancreatic neuroendocrine neoplasms (PanNENs) using radiofrequency ablation of the tumor under ultrasonography (EUS) guidance.

NCT ID: NCT03791346 Completed - Pancreatic Surgery Clinical Trials

Pancreatectomy for NET: External Evaluation of WHO 2017 Grading System

PanTEN
Start date: January 1, 1997
Phase:
Study type: Observational

Aim: The aim of this study was to investigate the clinicopathological factors and to evaluate the prognostic accuracy of the new World Health Organization (WHO) 2017 grading system in pancreatic neuroendocrine tumor (PanNET) patients. Methods: Data collected between 1997 and December 2017 were analyzed. Histological grading and staging was based on the WHO 2017 grading system. Outcome after surgery and predictors of overall survival (OS) and disease free survival (DFS) were evaluated.