Neuroendocrine Tumor Clinical Trial
Official title:
Gastrointestinal Motility in Patients With Neuroendocrine Tumors-Effects of Sandostatin LAR
We will study the total gastrointestinal transit time (GITT), gastric emptying and small
intestine motility in NET patients before and after treated with somatostatin analogues and
compare these to healthy subjects. For this we will use radio-opaque markers and the newly
developed Motility Tracking System (MTS).
Hypothesis: Patients with NET and carcinoid syndrome have decreased GITT, gastric emptying
and small bowel transit time and an increase in phase III MMC activity compared to healthy
subjects. Treatment with somatostatin analogues increase transit times and decrease phase
III MMC activity and improves the clinical symptoms.
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