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A Study of PM8002 Injection in Combination With Chemotherapy in Patients With NEN

Neuroendocrine Neoplasm Clinical Trial

Official title:
A Phase II Study to Evaluate the Efficacy, Safety and Pharmacokinetics of PM8002 Injection in Combination With Chemotherapy as Second Line Therapy in Unresectable Neuroendocrine Neoplasm

Clinical Trial Summary

PM8002 is a bispecific antibody targeting PD-L1 and VEGF. This study will evaluate the efficacy and safety of PM8002 in combination with FOLFIRI as second line treatment for neuroendocrine neoplasm (NEC and Ki-67≥55% G3 NET).

Clinical Trial Description

This is a phase II, single arm study assessing the efficacy and safety of PM8002 in combination with FOLFIRI as second line treatment for neuroendocrine neoplasm (NEC and Ki-67≥55% G3 NET) who failed first-line platinum-based chemotherapy ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05879055
Study type Interventional
Source Biotheus Inc.
Contact Jia Song
Phone +86 15921737659
Email song.j@biotheus.com
Status Recruiting
Phase Phase 2
Start date May 17, 2023
Completion date January 1, 2028
View Details
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