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Clinical Trial Summary

A Phase I open-label, multicenter study, to evaluate the safety, feasibility, and maximum tolerated dose (MTD) of treating children with newly diagnosed DIPG or recurrent neuroblastoma with molecular targeted therapy in combination with adoptive cell therapy (Total tumor mRNA-pulsed autologous Dendritic Cells (DCs) (TTRNA-DCs), Tumor-specific ex vivo expanded autologous lymphocyte transfer (TTRNA-xALT) and Autologous G-CSF mobilized Hematopoietic Stem Cells (HSCs)).


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT04837547
Study type Interventional
Source University of Florida
Contact G Bergendahl, MSN
Phone (704) 355-1220
Email genevieve.bergendahl@atriumhealth.org
Status Recruiting
Phase Phase 1
Start date September 20, 2021
Completion date September 2030

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