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Clinical Trial Summary

The purpose of the study is to evaluate safety and feasibility of neoadjuvant nivolumab plus ipilimumab prior to standard therapy (surgery, chemotherapy or radiation therapy) in patients with Neurofibromatosis Type 1 (NF1) and newly diagnosed pre-malignant and malignant peripheral nerve sheath tumors (MPNST) for whom surgery for resection of tumor is indicated.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT04465643
Study type Interventional
Source Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Contact Jaishri Blakeley, MD
Phone 410-955-8837
Email jblakel3@jhmi.edu
Status Recruiting
Phase Phase 1
Start date June 8, 2021
Completion date August 2026

See also
  Status Clinical Trial Phase
Withdrawn NCT01567787 - Proton Radiation Therapy for Spinal Tumors N/A