Thulium vs. Hol:YAG Laser

Status Completed

Clinical Trial Summary

This is a randomized prospective study to compare stone free rates and operative efficiency of two laser systems used during retrograde intrarenal surgery for kidney stone disease: 1. A superpulsed thulium fiber laser (thulium) 2. A pulse modulated high power holmium laser (Holmium)

Clinical Trial Description

This is a randomized prospective study. The purpose is to compare the stone free rate and operative efficiency of two leading contemporary laser systems used during retrograde intrarenal surgery for kidney stone disease. The researchers will compare the following two systems: 1. A superpulsed thulium fiber laser (thulium) 2. A pulse modulated high power holmium laser (Holmium) The researchers will recruit 82 subjects undergoing single stage unilateral ureteroscopy for renal stones with a volume between >5mm to < 20 mm. Subjects will be randomized to undergo lithotripsy with either Ho:YAG or Thulium lasers. All subjects will undergo surgical interventions that abide by broadly accepted guidelines and standards of care. The primary outcome is stone free rate evaluated by postoperative CT scans done 6-12 weeks after surgery. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05808257
Study type	Interventional
Source	Icahn School of Medicine at Mount Sinai
Contact
Status	Completed
Phase	N/A
Start date	January 7, 2022
Completion date	February 1, 2024

View Details

See also
Status	Clinical Trial	Phase
Enrolling by invitation	`NCT04746378` - PRedictive Accuracy of Initial Stone Burden Evaluation.
Recruiting	`NCT05100017` - Methocarbamol vs Oxybutynin for Management of Pain and Discomfort S/P Ureteroscopy Procedure	N/A
Recruiting	`NCT03692715` - Antibiotic Prophylaxis Before Shock Wave Lithotripsy	Phase 4
Completed	`NCT02547805` - Evaluate the Effect of ALLN-177 in Reducing Urinary Oxalate in Patients With Secondary Hyperoxaluria and Kidney Stones Over 28 Days	Phase 2
Completed	`NCT02289755` - Evaluating ALLN-177 for Reducing Urinary Oxalate Excretion in Calcium Oxalate Kidney Stone Formers With Hyperoxaluria	Phase 2
Completed	`NCT01690039` - Influence of Polymorphisms in the ATP6V1 Gene of the V-ATPase on the Development of Incomplete Distal Renal Tubular Acidosis
Completed	`NCT01650935` - Comparison of DASH With Oxalate Restricted Diet on Urine in Recurrent Stone Formers With Hyperoxaluria	N/A
Completed	`NCT01295879` - Vitamin D Repletion in Stone Formers With Hypercalciuria	Phase 4
Recruiting	`NCT05014178` - Kidney Sodium Functional Imaging
Not yet recruiting	`NCT06199102` - The High Initial Dose of Monitored Vitamin D Supplementation in Preterm Infants.	N/A
Recruiting	`NCT04367155` - Efficacy of Tranexamic Acid on Blood Loss During Percutaneous Nephrolithotomy.	N/A
Recruiting	`NCT04374188` - Efficacy of Ciprofloxacin Therapy in Avoidance of Sepsis in Patient Undergoing Percutanous Nephrolithotomy	N/A
Recruiting	`NCT05701098` - SOUND Pivotal Trial - (Sonomotion stOne comminUtion resoNance ultrasounD)	N/A
Recruiting	`NCT04389853` - Mini-PNCL vs fURS in Management of Nephrolithiasis	N/A
Completed	`NCT03348228` - Effect of Hydroxycitrate on Urine Chemistry	N/A
Completed	`NCT05350423` - Trial Assessing Renal Damage During Ureteroscopy	N/A
Completed	`NCT03454139` - Subcostal TAP Block For Percutaneous Nephrolithotomy	N/A
Recruiting	`NCT02279927` - Prospective Comparison Between Different Laser Settings for Ureteral \ Kidney Stones Treatment During Ureteroscopy	N/A
Completed	`NCT02276924` - Diagnostic Relevance of Laser Confocal Microscopy for the Screening of Upper Urinary Tract Tumors	N/A
Completed	`NCT00159393` - Percutaneous Nephrolithotomy: A Registry and Database