Narcolepsy Clinical Trial
Official title:
Feature of Polysomnography and Cerebral Metabolism and Function in Narcolepsy With/Without RBD and Control Subject
This study evaluates the PSG and cerebral metabolism and functions in narcolepsy with/without RBD
Polysomnographic (PSG) work-up one night to record nocturnal sleep condition in narcolepsy
with /without RBD and control subjects including sleep macrostructure, occurrence of sleep
onset rapid eye movement period(SOREMP), sleep stages distribution, and sleep arousle and leg
movement and apnea hyponea index would be calculated.
Functional magnetic resonance imaging (fMRI) has been used in human to nonivasiverlyn
investigate the neural mechanisms. This technique also apply to measures the variations in
brain perfusion, structure and morphology in narcolepsy patients by assessing the blood
oxygen level-dependent (BOLD) signal diffusion tensor imaging (DTI and voxel-based
morphometry(VBM)
This study compare the feature of PSG and fMRI between narcolepsy with RBD, narcolepsy
without RBD, control subject to evaluates the PSG and cerebral metabolism and functions in
narcolepsy with/without RBD.
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