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Myopia clinical trials

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NCT ID: NCT03193411 Completed - Lasik in Myopia Clinical Trials

Visumax Femtolasik Versus Moria M2 Microkeratome in Myopia

Start date: January 2014
Phase: N/A
Study type: Interventional

this is an interventional prospective clinical study which was conducted to evaluate the efficacy, safety, predictability, ocular aberrations, and flap thickness predictability of Visumax femtosecond laser (FSL) compared to Moria M2 microkeratome (MK) in mild to moderate myopia.

NCT ID: NCT03191942 Completed - Myopia Clinical Trials

Variation of Orthokeratology Lens Treatment Zone (VOLTZ) Study

Start date: June 20, 2017
Phase: N/A
Study type: Interventional

This project aims to study the effects of treatment characteristics on myopia control in orthokeratology by investigating the effects of modified treatment zone by reducing the lens back optic zone diameter on the effect of myopia control. The project will be a two-year randomized, double-masked (examiner - mask axial length only) study conducted at The Hong Kong Polytechnic University recruiting sixty Chinese subjects aged between 6-11. Subjects will be randomly assigned to two ortho-k groups. The Control group will wear KATT BeFree lens with a BOZD of 6mm while the Test group will wear KATT MC lens with a modified BOZD of 5mm.

NCT ID: NCT03174639 Completed - Retinal Detachment Clinical Trials

High Myopia Macular Hole and Retinal Detachment Treated With Double ILM Flaps

Start date: March 11, 2016
Phase: N/A
Study type: Interventional

From July 2015 to December 2015, clinical record of 8 consecutive cases of macular hole with retinal detachment in high myopia treated with combined inverted and free ILM flap insertion into the hole were retrospectively reviewed. The anatomical and function outcomes were assessed.

NCT ID: NCT03158142 Completed - Myopia Clinical Trials

The Influence of Atropine on Choroidal Thickness

Start date: March 15, 2017
Phase: Phase 4
Study type: Interventional

Atropine eye drops are increasingly prescribed for the management of progressive myopia or short-sightedness. A previous study suggested that the back of the eye or choroid may be a part of the mechanism by which it induces its effects. The aim of this study is to characterize the effects of atropine on choroidal thickness and the influence of time of administration (am vs pm). It is hypothesized that the atropine's effect on choroidal thickness will vary with baseline thickness related to diurnal rhythm, where thicker baseline thickness will show a reduced choroidal response.

NCT ID: NCT03152747 Recruiting - Cataract Clinical Trials

Influence of Posterior Vitreous Detachment on Retinal Detachment After Lens Surgery in Myopic Eyes

MYOPRED
Start date: May 3, 2017
Phase: N/A
Study type: Observational

Phacoemulsification with implantation of posterior chamber lenses represents the gold standard of care for patients needing lens surgery, but there is an increased risk of developing pseudophakic retinal detachment after surgery. Especially myopic patients have an even higher risk of pseudophakic retinal detachment compared to the general population. The aim of this multicenter study is to document the presence and/or post-operative development of posterior vitreous detachment (PVD) and to assess its influence on the incidence of retinal detachment (RD) in myopes in a time period of three and five years after lens surgery. 618 eyes of patients scheduled for regular lens surgery will be included, defined by an axial length of 25.0 mm or more. To examine the vitreous status, all patients will receive a comprehensive eye examination pre-operatively, including funduscopy with assessment of a Weiss ring and optical coherence tomography (OCT). Patients will be divided into two groups, group A with pre-operative complete PVD and group B with no/partial PVD. Group A will be invited for one follow-up visit (two months post-operatively) followed up by telephone interviews at one, two, three and five years after surgery to determine occurrence of pseudophakic retinal detachment. Group B will be invited for follow -up examinations at two months, six months and one year after surgery to document occurrence of PVD (if a PVD is present at one of the follow-ups, no more visits are necessary). Two, three and five years after surgery, all patients from group B will be interviewed by telephone, as in group A, to document the occurrence of pseudophakic retinal detachment. In the recent literature the association between the occurrence of PVD pre-/post-operative and RD after lens surgery is well documented but not described for myopic patients. The results of this multicenter study should help to tackle the problem of RD prediction in myopic patients depending on their pre-operative vitreous status, especially in the setting of refractive lens exchange.

NCT ID: NCT03142269 Completed - Clinical trials for Myopia, High, With Cataract and Anterior Capsule Polished

The Influences Of Anterior Capsule Polishing On Anterior Capsular Changes and Intraocular Lenses Stability of Super High Myopic Eyes

Start date: January 1, 2015
Phase: N/A
Study type: Interventional

A prospective study included 20 patients with super high myopia who underwent bilateral uneventful cataract. 360°anterior capsule polishing was performed with double-ended capsule polisher randomly in one eye, and the opposite unpolished was used as the control. The refractive state and size of anterior opening were measured at postoperative 1 day as the baseline. Then they followed up at 1 month, 3 months and 6 months after surgery to record refractive state, higher-order aberrations, size of anterior opening, tilt and decentration of IOL (intraocular lenses)and PAD(postoperative aqueous depth). The paired t test was used to compare the differences between the two groups, and the same test the postoperative follow-up comparing with the baseline.

NCT ID: NCT03140358 Active, not recruiting - Myopia Clinical Trials

The Use of Atropine 0.01% in the Prevention and Control of Myopia (ATOM3)

Start date: April 21, 2017
Phase: Phase 3
Study type: Interventional

Study of low dose atropine in preventing the onset and progression of myopia in high risk children with pre-myopia or low-myopia.

NCT ID: NCT03139201 Completed - Myopia Clinical Trials

Clinical Performance of the OxyAqua Daily Disposable Silicone Hydrogel Soft Contact Lens

Start date: September 21, 2016
Phase: N/A
Study type: Interventional

The objective of this study is to demonstrate that the OxyAqua silicone hydrogel soft contact lens could be prescribed as a supportive care for myopes.

NCT ID: NCT03135327 Recruiting - Multiple Sclerosis Clinical Trials

Clinical Applications of Advanced Ophthalmic Imaging

Start date: January 1, 2007
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the clinical application of advanced ophthalmic imaging devices such as optical coherence tomography (OCT), retinal function imager (RFI), slit-lamp biomicroscopy (SLB), PERG in diseased eyes and normal controls. There are two phases in this study. The first phase is an observational phase which studies the eye in various conditions. The second phase is an interventional phase which studies the changes in the eyes after taking an over-the-counter medical food (Ocufolin) for 6 months.

NCT ID: NCT03134599 Completed - Myopia Clinical Trials

Comparison of Clinical Performance and Subjective Preference of Three Contact Lenses

Start date: May 23, 2017
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the clinical performance and subject's preference out of three LRE (Limbal Ring Enhancing) lens types: etafilcon A (Johnson&Johnson), methafilcon A (Interozzo), and methafilcon A (CooperVision).