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Myopia clinical trials

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NCT ID: NCT04222842 Suspended - Clinical trials for Myopic Choroidal Neovascularisation

CM082 in Patients With Myopic Choroidal Neovascularization (CNV)

Start date: December 18, 2019
Phase: Phase 1
Study type: Interventional

This is a Phase I Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of Intermittent Oral Dosing of CM082 tablets in Chinese Patients With mCNV.

NCT ID: NCT02915133 Suspended - High Myopia Clinical Trials

The Relationship Between Structure and Visual Function in Myopia Foveoschisis

Start date: October 2016
Phase:
Study type: Observational

Macular foveoschisis (MF) is a common complication of pathological myopia, which is characterized by choroid-retinal degeneration and vision impairment. Although pars plana vitrectomy (PPV) is the primary method for MF treatment, there is still a large proportion of recurrent MF due to the extremely long global axial length and posterior staphyloma. Macular buckling (MB) surgery aims at counteracting the traction exerted by the posterior staphyloma, and has been proven an effective method for treating MF. Optical Coherence Tomography (OCT) is widely used for the structural analysis of MF. Multifocol electroretinogram (mfERG) is an objective examination for visual evaluation. To our knowledge, there is a lack of data on the comprehensive visual function evaluations of MF patients associated with OCT findings. Our clinical trial aims to provide the structural and functional relationship in MF patients undergoing MB surgery, and find out potential factors to determine the visual prognosis.