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Myopia clinical trials

View clinical trials related to Myopia.

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NCT ID: NCT06266910 Not yet recruiting - Myopia Clinical Trials

Effects of Autostereoscopic 3D Visual Training on Binocular Vision Function of Myopes

Start date: February 15, 2024
Phase: N/A
Study type: Interventional

This study intends to conduct a relatively comprehensive binocular visual function examination and follow-up on two groups of myopic subjects, one receiving autostereoscopic 3D vision training and the other receiving 2D vision training as a control. The aim is to explore the impact of autostereoscopic 3D vision training on the accommodation and convergence functions of myopes. Additionally, synchronized EEG-fNIRS signals will be collected to investigate whether changes in binocular visual function are accompanied by corresponding alterations in brain function.

NCT ID: NCT06265454 Not yet recruiting - Myopia Progression Clinical Trials

Low Dose Atropine Eye Drops in Myopic Egyptian Children

LAMP
Start date: September 1, 2024
Phase: Phase 2
Study type: Interventional

Previous Studies reported that low concentration atropine eye drops may be effective in increasing the choroidal blood flow and thickness and this slows myopia progression. purpose of the study is to compare changes in axial length, anterior chamber depth, choroidal thickness, central corneal thickness and anterior scleral thickness among myopic children receiving atropine 0.05% or 0.01% and placebo.

NCT ID: NCT06264830 Not yet recruiting - Cataract Clinical Trials

3D Visualization System in Highly Myopic Cataract Operation

3D-HiMCO
Start date: June 2024
Phase: N/A
Study type: Interventional

This study aims to investigate the impact of depth of field differences between the use of the 3D imaging system (NGENUITY® 3D Visualization System, Alcon, TX, USA) and conventional optical microscope in cataract surgery for highly myopic patients on intraoperative parameters and outcomes.

NCT ID: NCT06263946 Recruiting - Myopia Clinical Trials

Essilor® Stellest® Lenses Multicentre European Study (SLOMES)

SLOMES
Start date: March 22, 2024
Phase: N/A
Study type: Interventional

The goal of this post-market clinical follow up Study is to demonstrate the efficacy, safety, acceptability, and quality of life implications of Essilor® Stellest® spectacle lenses in slowing myopia progression in European children and adolescents. Participants will receive Essilor® Stellest® at inclusion visit and will be asked for a full time wear (>12 hours daily) for 24 months. The primary endpoints are the change in axial length and cycloplegic autorefraction from baseline to 24 months compared to expected change based on axial length and refraction centile positions at baseline.

NCT ID: NCT06251154 Completed - Myopia Clinical Trials

Clinical Comparison of Two Soft Contact Lenses

Start date: December 11, 2023
Phase: N/A
Study type: Interventional

This study was designed to gather short-term clinical performance data for 2 soft contact lenses.

NCT ID: NCT06250920 Completed - Myopia Clinical Trials

Effect of Virtual Reality-Based Visual Training for Myopia Control in Children

Start date: December 1, 2020
Phase: N/A
Study type: Interventional

To assess the efficacy and safety of virtual reality-based visual training (VRVT) in myopia control among children.

NCT ID: NCT06234189 Active, not recruiting - Myopia Clinical Trials

The Immediate Effect of Defocus Spectacles On the Choroid Thickness Using Optical Coherence Tomography on Children

TIDOCT
Start date: February 1, 2024
Phase: N/A
Study type: Interventional

The purpose is to examine temporary changes in the subfoveal choroid thickness after removal and after resumed use of Defocus Incorporated Multiple Segment Spectacle Lenses (DIMS).

NCT ID: NCT06232161 Active, not recruiting - Myopia Clinical Trials

Sustained Effect of Red-light Therapy for Myopia Control: A 2-Year Post-Trial Follow-up Study

Start date: May 13, 2020
Phase: N/A
Study type: Interventional

To evaluate the long-term efficacy and safety of red-light therapy for myopia control over 2 years, and the potential rebound effect after treatment cessation. The Chinese myopic children who originally completed the one-year randomised controlled trial in the previous study were enrolled. Children continued or started to daily usage of red-light therapy were defined as the RL group, while those who stopped using red-light therapy and switched to single-vision spectacles (SVS) as well as those who continued to keep single-vision spectacles in the second year were both regarded as the SVS group. Red-light therapy was provided by an at-home desktop light device emitting red-light of 650 nm and was administered for 3 min at a time, twice a day. Changes in axial length (AL) and cycloplegic spherical equivalence refraction (SER) are to be measured and compared as well as the adverse effects including the rebound effect. Red-light therapy has emerged as a novel myopia control treatment modality recently. A 12-month randomised controlled trial (RCT) conducted by our research team was thought to be earlier to evaluate the treatment of myopic children using red-light therapy. The trial demonstrated that PBM therapy was effective on myopia control, reducing axial elongation and spherical equivalence refraction (SER) progression 103% and 127% compared with single vision spectacle (SVS) over a 12-month period, respectively. The promising efficacy of red-light therapy has been further confirmed in other studies. In addition, satisfactory user acceptability and no unrecovered functional and structural damages were observed. Myopia generally progresses throughout childhood and hence a study duration of 1 year is not sufficient to widely adopt the red-light therapy as a treatment strategy for myopia control. The sustainability of treatment efficacy, rebound phenomenon upon cessation of treatment, and potential risks and adverse effects in myopic children with longer-term PBM therapy, remain to be fully elucidated. Thus, the aims of this post-trial follow-up study were to invite the participants to come back for a 24-month visit and to investigate the long-term efficacy and safety of continued red-light therapy as well as the potential rebound effect following red-light treatment cessation.

NCT ID: NCT06229301 Recruiting - Myopia Clinical Trials

A Study of Artificial Intelligence Assisted Small Incision Lenticule Extraction (SMILE) for Surgical Design and Influencing Factors

Start date: March 1, 2014
Phase:
Study type: Observational

The goal of this observational study is to learn about the difference of refractive outcomes between Artificial Intelligence and experienced surgeon predicting Nomogram assist SMILE surgical design and the influenced factors of refractive outcomes in patients who underwent Small Incision Lenticule Extraction(SMILE) at the Refractive Surgery Center of Tianjin Eye Hospital. The main questions it aims to answer are: - Compare the difference of refractive outcomes between Artificial Intelligence and experienced surgeon predicting Nomogram assist SMILE surgical design - Analysis the influenced factors of refractive outcomes

NCT ID: NCT06229119 Not yet recruiting - Nearsightedness Clinical Trials

Vault Evaluation After ICL Implantation

Start date: January 29, 2024
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate the lens vault after implantation of an implantable collamer lens (ICL). The ICL is designed to be implanted in front of the eye, without removing the natural lens. Because of this, it is also known as a phakic IOL. The ICL has already been approved by the U.S. Food and Drug Administration (FDA) to treat mid to high degrees of refractive errors such nearsightedness (also called myopia) with or without astigmatism. Once the artificial lens is implanted, a space between the ICL and the crystalline lens is created, which is called vault.