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Myopia clinical trials

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NCT ID: NCT06058780 Completed - Myopia Clinical Trials

Safety and Efficacy of Implantable Collamer Lens Versus Implantable Phakic Lens IPCL in Myopic Patients; A Comparative Study

Start date: August 1, 2021
Phase: N/A
Study type: Interventional

Phakic intraocular lenses (pIOL) have proven to be a great alternative to corneal refractive surgery in certain situations. They offer several advantages over corneal techniques, such as being suitable for high myopes and causing relatively fewer higher-order aberrations. In addition, pIOLs have been shown to provide better retinal image magnification and higher contrast sensitivity compared to laser in situ keratomileusis, regardless of whether the myopia is low or high.

NCT ID: NCT06046209 Completed - Myopia Clinical Trials

Comparing a Monthly Replacement Lens Versus a Daily Disposable Lens

Start date: September 28, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to compare subjective ratings of lens handling at insertion for a monthly replacement lens versus a daily disposable lens in habitual soft lens wearers.

NCT ID: NCT06045325 Completed - Myopia Clinical Trials

Assessment of Measurement Variability Across Automated Biometry Devices

Start date: July 25, 2023
Phase:
Study type: Observational

This is a non-interventional prospective, comparative study of white-to-white, corneal thickness, and anterior chamber depth measurements as taken on the Orbscan II compared to the IOL Master 700 (Zeiss), IOL Master 500 (Zeiss), Atlas 9000 (Zeiss), Lenstar 900 (Haag-Streit), Argos (Alcon), iTrace (Tracey), Pentacam (Oculus), and manual calipers.

NCT ID: NCT05967702 Completed - Myopia Clinical Trials

A 3-year Cross-sectional Assessment of the Tianjin Child and Adolescent Large-scale Eye Study

Start date: July 1, 2019
Phase:
Study type: Observational

This is a school-based, cross-sectional study to assess the incidence and prevalence, risk factors of myopia among schoolchildren in both eye-use environment, eye-use habits, lifestyle, and family and subjective factors before and during COVID-19. Large population and representative study subjects. Environmental exposure and daily within and out-of-school activities will be evaluated in a random subgroup.

NCT ID: NCT05959200 Completed - Myopia Clinical Trials

Clinical Performance Evaluation of Two Frequent Replacement Silicone Hydrogel Toric Contact Lenses

Start date: August 14, 2023
Phase: N/A
Study type: Interventional

The primary objective of this study is to evaluate the axis orientation of LID226397 toric contact lenses.

NCT ID: NCT05957458 Completed - Myopia Clinical Trials

Myopia Control With Three Lever Irradiance of PBM Therapy in Children and Adults

MCPT
Start date: January 1, 2021
Phase: N/A
Study type: Interventional

Photobiomodulation therapy, that is, Low-level red-light technology provides a new and innovative myopia control approach. This strategy enables relatively high energies of light to be delivered at much shorter durations of exposure to induce the myopia control effect. The efficacy of the low-level red-light technology has been proven in a Chinese populationb for the recent 3 years with evidence based papers and amazing results. However, there's not yet evidence to demonstrate the relationship between the dose response effect of photobiomodulation therapy on myopia control at the different age lever.

NCT ID: NCT05956704 Completed - Myopia Clinical Trials

The Different Design of Orthokeratology

Start date: December 1, 2020
Phase: N/A
Study type: Interventional

In this study, we intend to enroll orthokeratology subjects aged 8-18 years old with binocular myopia up to and including -4.00 D. They were randomly selected to wear both orthokeratology of different designs, one with an aspheric wide inversion zone design in the optical zone and the other with a traditional spherical curved segment design, and to investigate the differences between these two lenses in terms of their effectiveness in myopia retardation, defocus, and aberration.

NCT ID: NCT05917041 Completed - Children Myopia Clinical Trials

Exploratory Study of SAT-001 in Treatment of Pediatric Patient With Myopia

Start date: March 5, 2021
Phase: N/A
Study type: Interventional

The Purpose of this study is to explore the safety and effectiveness of SAT-001, a medical device for the treatment of myopia in pediatric patient with myopia

NCT ID: NCT05852782 Completed - Myopia Clinical Trials

Effects of Light on the Choroid and Pupil

Start date: February 1, 2019
Phase: N/A
Study type: Interventional

Monochromatic light creates longitudinal chromatic aberration, with short wavelength blue light forming a focal point in front of the retina and long wavelength red light forming a focal point behind the retina. The investigators hypothesize that such chromatic aberrations, induced by exposure to red or blue LED lights, will cause the choroid behind the retina to respond to bring the image into focus by modulating its thickness, either thickening in the case of blue light or thinning in the case of red light. The magnitude and direction of this response is difficult to predict as previous studies have shown opposite findings in non-human primates and rodents. Furthermore, the investigators hypothesize that exposure to red or blue light will induce changes in how the pupil responds to light, because the cells in the eye that are involved in pupil control are most sensitive to blue light.

NCT ID: NCT05835115 Completed - Myopia Clinical Trials

Development and Validation of a Deep Learning-based Myopia and Myopic Maculopathy Detection and Prediction System

Start date: April 1, 2022
Phase:
Study type: Observational

Myopia has become a global public health issue. Myopia affects the psychological health of children and adolescents and poses a financial burden. Therefore, early detection and prediction of children at a high risk of myopia development and progression are critical for precise and effective interventions. In this study, we developed a deep learning system DeepMyopia, based on fundus images with the following objectives: 1) to predict myopia onset and progression; 2) To detect myopic macular degeneration for AI-assisted diagnosis; 3) To predict the development of myopic macular degeneration; 4) evaluate its cost-effectiveness.