Myopia, Progressive Clinical Trial
Official title:
Eye Drops Study for Myopia Control in Schoolchildren
The myopia prevalence in schoolchildren is high in Taiwan. The myopia progression is fast in children and often associated high myopia in later life. This prospective and randomized study to investigate the effect of myopia control in myopic children with ultra low concentrations of atropine eye drops and/or low concentrations of anti-allergic and inflammatory eye drops.
Myopia onset earlier in children who would suffer a high degree of myopia in the future
adulthood.and higher risk for retinal detachment, macular degeneration, and even blindness.
In Taiwan, myopia macular degeneration is the first place of irreversible blind cause in the
elderly. The evidence based medicine shows atropine is the most effective treatment for the
progression of myopia so far, but the side effects including photophobia and near blurred
vision often disturbing patients and resulting poor compliance and high drop-out rate.
Recently, the studies from Taiwan and Singapore showed that low concentrations of atropine
(0.05% or 0.01%) can effectively inhibit the myopia progression, reduce the symptoms of
photophobia, and to achieve favorable myopia control. Previous study found that myopia and
allergic conjunctivitis and inflammation were related. The investigators designed a
prospective and randomized study to investigate the effect of myopia control in myopic
children with ultra low concentrations of atropine eye drops and/or low concentrations of
anti-allergic and inflammatory eye drops. Due to environmental factors such as near work,
after school class and outdoor activity are also great associated with myopia, the
questionnaires also are collected in this study.
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