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NCT06312891 Clinical Trial

Value of Heart Rate Lowering Therapy in Acute Myocarditis

Myocarditis Clinical Trial

Official title:
Value of Heart Rate Lowering Therapy in Acute Myocarditis

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT06312891
Other study ID # VOHRLTIAM
Secondary ID
Status Recruiting
Phase
First received
Last updated
Start date April 1, 2024
Est. completion date June 1, 2025

Study information
Verified date March 2024
Source Assiut University
Contact sara mahmoud
Phone 01016862195
Email saramahmoud199783@gmail.com
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

To study the value of heart rate lowering therapy "pharmacological rest" on the short term in cases of myocarditis without LV dysfunction.

Recruitment information / eligibility
Status Recruiting
Enrollment 150
Est. completion date June 1, 2025
Est. primary completion date April 1, 2025
Accepts healthy volunteers No
Gender All
Age group 18 Years to 90 Years
Eligibility Inclusion Criteria: - Adults: =18 years of age. - Presentation: at least one of the following: - Myopericarditis/ACS-like - MINOCA - Arrhythmias: brady or tachyarrhythmias. - Unexplained compensated acute cardiomyopathy (excluded ischemic, valvular, hypertensive, metabolic, and toxic causes of cardiomyopathy as indicated clinically). - TTE: LVEF>40% - CMR-confirmed myo(peri)carditis (Lake Louise criteria) Exclusion Criteria: - • Rheumatic carditis. - Connective tissue diseases (-ve ANA). - Cancer chemotherapy. - Toxicity from immunotherapy. - Vaccine-related myocarditis. - Presence of coronary artery disease. - Peripartum (occurring during the last month of pregnancy or within 5 months after delivery) - ECG: atrial fibrillation/flutter. - Resuscitated sudden death. - Early/initial phase of decompensated heart failure. - Tamponade complicating pericarditis unless successfully managed.

Study Design

Related Conditions & MeSH terms

Intervention

Drug:
• Ivabradine
heart rate lowering therapy

Locations
Country Name City State
Egypt Heart Hospital Assiut

Sponsors (1)
Lead Sponsor Collaborator
Assiut University

Country where clinical trial is conducted

Egypt, 

Outcome
Type Measure Description Time frame Safety issue
Primary Value of Heart Rate Lowering Therapy in Acute Myocarditis To study the value of heart rate lowering therapy "pharmacological rest" on the short term in cases of myocarditis without LV dysfunction. baseline
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