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Clinical Trial Summary

Mycoplasma pneumoniae is one of the most common causes of community-acquired pneumonia in children. The clinical course is typically self-limited and benign; however, rare cases of severe pneumonia can develop despite appropriate antibiotic therapy. The investigators aim to study the effects of prednisolone on severe M. pneumoniae pneumonia with lobar consolidation or pleural effusion in children.


Clinical Trial Description

Mycoplasma pneumoniae is one of the most common causes of community-acquired pneumonia in children. The clinical course is typically self-limited and benign; however, rare cases of severe pneumonia can develop despite appropriate antibiotic therapy. The investigators aim to study the effects of prednisolone on severe M. pneumoniae pneumonia with lobar consolidation or pleural effusion in children. Participants will be randomly assigned (1:1 ratio) to receive either prednisone 1 mg/kg/d daily for 5 days or none. The primary endpoint was fever duration and analysed by intention to treat. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT02618057
Study type Interventional
Source Seoul National University Hospital
Contact Ki Wook Yun, M.D., Ph.D.
Phone 82-2-2072-4909
Email pedwilly@gmail.com
Status Recruiting
Phase Phase 4
Start date June 2016
Completion date December 2020

See also
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Not yet recruiting NCT06325293 - A Trial of Placebo Versus Macrolide for Mycoplasma Pneumoniae Childhood Pneumonia: MYTHIC Study N/A
Completed NCT02303587 - Methylprednisolone for Children With Severe Mycoplasma Pneumoniae Pneumonia (MCMP) N/A