Musculoskeletal Pain Clinical Trial
Official title:
Examining Osteopathic Manipulation on Making a Neuropsychological Brain of Difference in Adults With Pain: A BOD Study Protocol and Rationale for a New Approach
Patients with pain commonly experience cognitive impairment. While symptoms of pain are effectively treated with osteopathic manipulative treatment (OMT), the cognitive piece is vastly ignored. Pain-induced cognitive dysfunction can be severe and is particularly apparent in working memory and attention. There is good reason to also expect cognitive responsiveness to OMT. Previous research has already reported related psychiatric outcomes, including relief from stress, self-perception and anxiety, suggesting that OMT may produce more global effects on cortical processing than currently thought.
Patients with pain commonly experience cognitive impairment. While symptoms of pain are effectively treated with osteopathic manipulative treatment (OMT), the cognitive piece is vastly ignored. Previous research has already reported related psychiatric outcomes, including relief from stress, self-perception and anxiety, suggesting that OMT may produce more global effects on cortical processing than currently thought. The current study is designed to extend previous research in several ways: 1. To describe the neuropsychological (NP) characteristics of adults with pain within an osteopathic and allopathic setting 2. To correlate NP with clinical outcomes (pain severity, number/location of osteopathic lesions) 3. To determine if OMT is associated with improved NP function. 4. To use saliva to measure cytokine concentration of IL-1β,IL-6, IL-8, TNF-α 5. To correlate cytokine concentrations with clinical outcomes (pain severity, number/location of osteopathic lesions, NP) ;
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