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Clinical Trial Summary

Patients with pain commonly experience cognitive impairment. While symptoms of pain are effectively treated with osteopathic manipulative treatment (OMT), the cognitive piece is vastly ignored. Pain-induced cognitive dysfunction can be severe and is particularly apparent in working memory and attention. There is good reason to also expect cognitive responsiveness to OMT. Previous research has already reported related psychiatric outcomes, including relief from stress, self-perception and anxiety, suggesting that OMT may produce more global effects on cortical processing than currently thought.


Clinical Trial Description

Patients with pain commonly experience cognitive impairment. While symptoms of pain are effectively treated with osteopathic manipulative treatment (OMT), the cognitive piece is vastly ignored. Previous research has already reported related psychiatric outcomes, including relief from stress, self-perception and anxiety, suggesting that OMT may produce more global effects on cortical processing than currently thought. The current study is designed to extend previous research in several ways: 1. To describe the neuropsychological (NP) characteristics of adults with pain within an osteopathic and allopathic setting 2. To correlate NP with clinical outcomes (pain severity, number/location of osteopathic lesions) 3. To determine if OMT is associated with improved NP function. 4. To use saliva to measure cytokine concentration of IL-1β,IL-6, IL-8, TNF-α 5. To correlate cytokine concentrations with clinical outcomes (pain severity, number/location of osteopathic lesions, NP) ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04058431
Study type Interventional
Source Midwestern University
Contact
Status Active, not recruiting
Phase N/A
Start date January 2017
Completion date January 2026

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