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Pilot Study of Growth Hormon to Treat SMA Typ II and III

Muscular Atrophy, Spinal Clinical Trial

Official title:
Can Treatment With Human Growth Hormone Increase Strength in Spinal Muscular Atrophy Type II and III?

Clinical Trial Summary

The purpose of this study is to determine whether Growth hormon can increase strength in spinal muscular atrophy type II and III.

Clinical Trial Description

This pilot study is planned as a placebo-controlled cross-over trial in a limited number of patients. It is the aim to investigate the effect of GH on the short-term changes of strength and to investigate the tolerability of the treatment. If the results of the study are positive, further studies of longer duration addressing the development of motor function and quality of life could follow ;

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00533221
Study type Interventional
Source University Hospital Freiburg
Contact
Status Completed
Phase Phase 2
Start date October 2007
Completion date August 2011
View Details
See also
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