Muscle Weakness Clinical Trial
— HLSOfficial title:
Achilles Tendon Homograft for the Treatment of Gluteus Medius Insufficiency After Hip Replacement
NCT number | NCT05206838 |
Other study ID # | 276262 |
Secondary ID | |
Status | Recruiting |
Phase | N/A |
First received | |
Last updated | |
Start date | June 29, 2022 |
Est. completion date | December 2026 |
Verified date | November 2023 |
Source | Sahlgrenska University Hospital, Sweden |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
Residual limping after total hip arthroplasty is a serious complication that lacks effective treatment. The purpose of this study is to evaluate a surgical treatment for residual limping and compare its results with non-surgical treatment. Our hypothesis is that surgical treatment followed by physiotherapy increases hip function and reduces limping compared with non-surgical treatment with physiotherapy alone.
Status | Recruiting |
Enrollment | 44 |
Est. completion date | December 2026 |
Est. primary completion date | December 2026 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 40 Years to 80 Years |
Eligibility | Inclusion Criteria: - Persisting limping with positive Trendelenburg's sign for at least 12 months after total hip arthroplasty - Rupture/avulsion of the gluteus medius tendon verified with ultrasound or MRI - Leg length discrepancy of less than 1 cm - Femoral offset discrepancy of less than 25% Exclusion Criteria: - Neuromuscular disorders |
Country | Name | City | State |
---|---|---|---|
Sweden | Sahlgrenska University Hospital | Mölndal |
Lead Sponsor | Collaborator |
---|---|
Sahlgrenska University Hospital, Sweden | Göteborg University, The Gothenburg Society of Medicine, Vastra Gotaland Region |
Sweden,
Beard DJ, Harris K, Dawson J, Doll H, Murray DW, Carr AJ, Price AJ. Meaningful changes for the Oxford hip and knee scores after joint replacement surgery. J Clin Epidemiol. 2015 Jan;68(1):73-9. doi: 10.1016/j.jclinepi.2014.08.009. Epub 2014 Oct 31. — View Citation
Ewen AM, Stewart S, St Clair Gibson A, Kashyap SN, Caplan N. Post-operative gait analysis in total hip replacement patients-a review of current literature and meta-analysis. Gait Posture. 2012 May;36(1):1-6. doi: 10.1016/j.gaitpost.2011.12.024. Epub 2012 Mar 10. — View Citation
Fehm MN, Huddleston JI, Burke DW, Geller JA, Malchau H. Repair of a deficient abductor mechanism with Achilles tendon allograft after total hip replacement. J Bone Joint Surg Am. 2010 Oct 6;92(13):2305-11. doi: 10.2106/JBJS.I.01011. — View Citation
Whiteside LA, Roy ME. Incidence and treatment of abductor deficiency during total hip arthroplasty using the posterior approach: repair with direct suture technique and gluteus maximus flap transfer. Bone Joint J. 2019 Jun;101-B(6_Supple_B):116-122. doi: 10.1302/0301-620X.101B6.BJJ-2018-1511.R1. — View Citation
Whiteside LA. Surgical technique: Transfer of the anterior portion of the gluteus maximus muscle for abductor deficiency of the hip. Clin Orthop Relat Res. 2012 Feb;470(2):503-10. doi: 10.1007/s11999-011-1975-y. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Oxford Hip Score (OHS) | Patient-reported hip function measured in a scale 0-48 | 12 months | |
Secondary | Trendelenburg's sign | Presence or abscence of Trendelenburg's sign as binary outcome (yes/no) | 12 months | |
Secondary | Hip abduction torque | Abduction torque in the frontal plane measured in Nm/Kg with gait analysis | 12 months | |
Secondary | University of California Level of Activity (UCLA) | Patient-reported activity level measured with in a rank scale 0-10 | 12 months | |
Secondary | Euroqol 5 dimension 5 level index (EQ5D-5L) | Patient-reported health-related quality of life measured with swedish version of the euroqol 5 dimension 5 level index in a scale 0-1 | 12 months | |
Secondary | Euroqol visual analog scale (EQVAS) | Patient-reported health-related quality of life measured with the euroqol visual analog scale 0-100 | 12 months | |
Secondary | Adverse events | All complications resulting in contact with health care provider within one year. | 12 months |
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT05543980 -
Leg Heat Therapy in Elderly Individuals
|
Phase 2 | |
Enrolling by invitation |
NCT03297632 -
Improving Muscle Strength, Mass and Physical Function in Older Adults
|
N/A | |
Completed |
NCT04207359 -
Effects of Creatine Supplementation in Breast Cancer Survivors
|
N/A | |
Completed |
NCT06216015 -
Exercise Training and Kidney Transplantation
|
N/A | |
Completed |
NCT04076982 -
Effect of Supplementary Dietary Protein (21g Per Day) on Lean Mass and Strength in Sedentary, Adult Vegetarians
|
N/A | |
Not yet recruiting |
NCT03662555 -
Effect of Neuromuscular Electrical Stimulation Combined With Blood Flow Restriction on Muscular and Cardiovascular Function
|
N/A | |
Completed |
NCT02530723 -
Functional Changes and Power Training in Older Women.
|
N/A | |
Completed |
NCT01704976 -
SR-WBV Training for Frail Elderly in the Skilling up Stage
|
N/A | |
Completed |
NCT01743495 -
CAPABLE for Frail Dually Eligible Older Adults
|
N/A | |
Completed |
NCT00183040 -
HORMA: Hormonal Regulators of Muscle and Metabolism in Aging
|
Phase 2 | |
Enrolling by invitation |
NCT06432062 -
Investigation the Effect of Rectus Abdominis and Erector Spinae Muscle Fatigue on the Viscoelastic Properties of Thoracolumbal Fascia
|
||
Recruiting |
NCT05073224 -
Muscle Function After Childbirth
|
N/A | |
Completed |
NCT04956705 -
Vitamin D and Calcium Supplementation at Danish Nursing Homes
|
N/A | |
Recruiting |
NCT03810768 -
Metabolomics Study on Postoperative Intensive Care Acquired Muscle Weakness
|
||
Completed |
NCT00060970 -
Evaluating Muscle Function After Ankle Surgery
|
N/A | |
Completed |
NCT04546048 -
The Early Strength Training Program in Post-transplant Liver Cases
|
N/A | |
Completed |
NCT03628365 -
Can Beta-Hydroxy-beta-Methylbutyrate Supplementation Counteract Muscle Catabolism in Critically Ill Patients?
|
N/A | |
Completed |
NCT05056298 -
Effect of Insole Added to Exercise in Patients With Bilateral Flexible Flatfoot
|
N/A | |
Completed |
NCT02739464 -
Effect of In-Patient Exercise Training on Length of Hospitalization in Burned Patients
|
N/A | |
Completed |
NCT05497960 -
Vivo Prediabetes Study: Online, Live, and Interactive Strength Training for Older Adults With Prediabetes
|
N/A |