Comparison of the Increment of Neuromuscular Parameters in Vegetarians and Non-vegetarians

Muscle Strength Clinical Trial

Official title:

Comparison of Strength and Muscle Thickness of Recreational Sports Individuals With Vegetarian or Non-vegetarian Food Standards Adequate in Proteins

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03785002
• Other study ID #: 69787617.0.0000.5327
• Status: Completed
• Phase: N/A
• Start date: February 20, 2018
• Est. completion date: June 30, 2019

Study information

• Verified date: May 2020
• Source: Hospital de Clinicas de Porto Alegre
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

A strength training session promotes increased muscle sensitivity to protein synthesis, which lasts for 24 hours after its closure. Recent studies have shown that the subsequent intake to the training session of approximately 20g or 0.24g / kg of high-quality protein in the same meal induces a plateau in this synthesis. Thus, this study aims to compare the muscular strength between vegetarian and omnivorous athletes with adequate protein intake to reach this plateau. It will recruit 64 university sportsmen who have maintained vegetarian or omnivorous diet for at least 6 months, totalizing 32 individuals per group. After signing the Term of Consent, participants will be submitted to anthropometric and body composition assessment (via DEXA), neuromuscular tests [(ie, muscle strength - 1RM, peak torque of knee extensors (JE), muscle thickness of JE and cohort analysis (ANCOVA) will be used in order to compare the results of the study, and to compare the results of the covariance analysis (ANCOVA). the levels of the neuromuscular parameters between the groups, considering the initial values of the force and the initial muscular thickness as covariables, the other parameters will be presented in the form of mean and standard deviation or median, the differences will be considered significant for values of p <0, 05. Expected to find no differences in strength and muscle thickness between vegetarians and omnivores after adequate protein intake.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 64
• Est. completion date: June 30, 2019
• Est. primary completion date: June 30, 2019
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 19 Years to 60 Years

Eligibility

Inclusion Criteria:

• Be over the age of 19 and under 60;

• Have BMI <30 kg / m²;

• Be vegetarian or omnivorous for at least 6 months;

• Have not exercised regularly for at least 6 months.

• Be available to practice bodybuilding at School of Physical Education, Physiotherapy and Dance, 2x / week, for 3 months, free (times to combine).

Exclusion Criteria

• Be vegan, vegetarian lacto or vegetarian egg

• Be a carrier of chronic diseases;

• Present physical limitations or musculoskeletal problems, which contraindicate the performance of strength exercises;

• Failure to adhere to the proposed dietary modifications, relating to the adequacy of the portion of protein per meal, due to financial unfeasibility (low income condition);

• Use of protein or amino acid, caffeine or other thermogenic food supplements.

Related Conditions & MeSH terms

• Dietary Proteins
• Hypertrophy
• Muscle Strength
• Strength Training

Intervention

Other:
• Strength training
24 strength training sessions, with approximately 1 hour duration, that will occur 2x/week
• Protein intake
Guidance on the adequacy of protein intake (at least 20g of protein in breakfast, lunch and dinner)

Locations

Country	Name	City	State
Brazil	Gabriela Luccciana Martini	Porto Alegre	Rio Grande Do Sul

Sponsors (1)

Lead Sponsor	Collaborator
Hospital de Clinicas de Porto Alegre

Country where clinical trial is conducted

Brazil, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Muscle Thickness (mm)	To compare muscle thickness (mm) of the femoral quadriceps by Ultrasound, among vegetarian and omnivorous participants.	At the14th week of study participation.
Secondary	Maximal strength (kg)	To compare maximal strength (kg), using the one- repetition maximum test (1RM) for bilateral knee extension exercises. Each subject's maximal load was determined with no more than five attempts and an adequate amount of recovery time was permitted between each attempt (3-5min). Each valid repetition was considered when subjects performed full knee extension with proper technique.	At the 14th week of study participation.
Secondary	Isometric peak torque (PTiso) (N.m)	To compare knee extensors Isometric peak torque (N.m), defined as the highest value of the torque recorded during unilateral knee extension, using an isokinetic dynamometer, among vegetarian and omnivorous participants.	At the 14th week of study participation.
Secondary	Body fat free mass (g)	To compare body fat free mass by Dual-energy x-ray absorptiometry (DEXA) evaluation, of omnivorous and vegetarian participants.	At the 14th week of study participation
Secondary	Body fat mass (g)	To compare body fat mass by Dual-energy x-ray absorptiometry (DEXA) evaluation, of omnivorous and vegetarian participants.	At the14th week of study participation.
Secondary	Protein intake (g)	To compare daily protein intake (g) assessed by 24 hour reminder, applied in interview conducted by nutritionist, of omnivorous and vegetarian participants.	At the 14th week of study participation.