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Muscle Spasticity clinical trials

View clinical trials related to Muscle Spasticity.

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NCT ID: NCT02052024 Completed - Stroke Clinical Trials

Myobloc Atrophy Study

MAS
Start date: May 2014
Phase: Phase 4
Study type: Interventional

The present pilot study is designed to assess the extent to which BOTOX and MYOBLOC cause muscle atrophy in spastic patients. The primary objective is to assess whether there is statistically significant difference in muscle atrophy between the two groups over a one year period.

NCT ID: NCT02043145 Completed - Muscle Spasticity Clinical Trials

Safety and Efficacy of BOTOX® (Botulinum Toxin Type A) in Korea

Start date: July 2008
Phase: N/A
Study type: Observational

This post marketing surveillance study in Korea will evaluate the safety and efficacy of BOTOX (botulinum toxin Type A) in patients who receive treatment according to standard of care for primary axillary hyperhidrosis, focal spasticity or moderate to severe glabellar lines in clinical practice.

NCT ID: NCT02027025 Completed - Spasticity Clinical Trials

Study of SPARC1103 in Subjects With Spasticity

Start date: April 21, 2014
Phase: Phase 2
Study type: Interventional

Study of SPARC1103 in subjects with spasticity

NCT ID: NCT02020980 Completed - Clinical trials for Lower Limb Spasticity

RELIEF Study: Lower Limb Pain Relief After Injection Cycles in Adults Suffering From Lower Limb Spasticity Following Stroke

RELIEF
Start date: April 2014
Phase:
Study type: Observational

The objective of this study is to demonstrate the effect of intramuscular BoNT-A injections in relieving pain, in a broad population of patients who suffer pain as the primary problem associated with spasticity. Thus, this study will help to expand the information that is available regarding the impact of BoNT-A treatment in routine clinical practice conditions. Treatment goals can vary greatly from one patient to another and there is no unique, single outcome that reflects the treatment benefits in all the cases. Therefore, this study with special focus on the achievement of therapeutic goals, will allow the identification of each patient's specific goals regarding the improvement of the functional outcomes, the quality of life and patient well-being.

NCT ID: NCT02002884 Completed - Cerebral Palsy Clinical Trials

Dose-response Study of Efficacy and Safety of Botulinum Toxin Type A to Treat Spasticity of the Arm(s) or of Arm(s) and Leg(s) in Cerebral Palsy

XARA
Start date: March 28, 2014
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine whether injections of Botulinum toxin type A into muscles of one or both arms alone or in combination with injections into one or both legs are effective and safe in treating children/adolescents (age 2-17 years) with increased muscle tension/uncontrollable muscle stiffness (spasticity) due to cerebral palsy.

NCT ID: NCT01968902 Completed - Multiple Sclerosis Clinical Trials

Safety of Xeomin for Lower Limb Spasticity in Multiple Sclerosis Patients

Start date: November 2013
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine if Xeomin® will prove effective for significantly improving lower extremity spasticity and will be well tolerated by the majority of MS patients.

NCT ID: NCT01964547 Completed - Multiple Sclerosis Clinical Trials

A Randomized Study of Sativex on Cognitive Function and Mood: Multiple Sclerosis Patients

Start date: January 2012
Phase: Phase 4
Study type: Interventional

A study to compare the change in cognitive performance and psychological status of patients with spasticity due to Multiple Sclerosis when treated with Sativex or placebo, added to existing anti-spasticity therapy over a period of 48 weeks. Secondary objectives were to evaluate the effect of Sativex on mood and spasticity and to assess the safety and tolerability of Sativex.

NCT ID: NCT01945684 Completed - Stroke Clinical Trials

A Randomized, Double Blind, Multi-center, Active Drug Controlled, Phase III Clinical Trial to Compare the Safety and Efficacy of DWP450 Versus Botox® in Treatment of Post Stroke Upper Limb Spasticity

Start date: September 2013
Phase: Phase 3
Study type: Interventional

Purpose: This study is a Randomized, Double Blind, Multi-center, Active Drug Controlled, Phase III Clinical Trial to Compare the Safety and Efficacy of DWP450 Versus Botox® in Treatment of Post Stroke Upper Limb(wrist, finger, elbow, thumb)Spasticity.

NCT ID: NCT01930786 Completed - Muscle Spasticity Clinical Trials

An Adult Spasticity Registry of OnabotulinumtoxinA Treatment

ASPIRE
Start date: October 16, 2013
Phase:
Study type: Observational

This is a registry study in adults with spasticity to determine onabotulinumtoxinA use in clinical practice. Treatment will be administered in accordance with physician standard practice. All treatment decisions lie with the physician.

NCT ID: NCT01915459 Completed - Stroke Clinical Trials

Phase III Study of Botulax® to Treat Post Stroke Upper Limb Spasticity

Start date: June 2013
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the safety and efficacy of Botulax® compared to Botox® reducing upper limb muscle tone in post stroke patients.