Clinical Trials Logo
  1. Home
  2. Muscle Injury
  3. NCT03782389

The Role of Periodic Health Examination in Determining Indirect Muscle Injury Risk in Elite Football (Soccer)

Muscle Injury Clinical Trial

Official title:
The Role of Periodic Health Examination in Determining Lower Extremity Muscle Injury Risk in Elite Football (Soccer): A Protocol for an Investigation Into Multivariable Prognostic Model Development, Validation and Prognostic Factor Exploration

Clinical Trial Summary

Preseason periodic health examination (PHE) is used routinely in elite football (soccer) and can be used to inform injury prevention strategies. Indirect muscle injuries (IMI) are a considerable burden to elite teams. This investigation aims to evaluate whether measurements from PHE can be used in a multivariable model to predict IMI risk in elite players, or to establish prognostic factors that are associated with IMIs.

Clinical Trial Description

BACKGROUND Indirect muscle injuries (IMIs) are a considerable burden to elite football (soccer) teams and prevention of these injuries offers many benefits. Preseason medical, musculoskeletal and performance screening (termed periodic health examination (PHE)) is used to help determine players at risk of injuries such as IMIs, where identification of PHE-derived prognostic factors (PF) may inform IMI prevention strategies. Furthermore, using several PFs in combination within a multivariable prognostic model may allow individualised IMI risk estimation and specific targeting of prevention strategies, based upon an individual's PF profile. No such models have been developed in elite football and the current IMI prognostic factor evidence is limited. This study aims to: 1) to develop and internally validate a prognostic model for individualised IMI risk prediction during a season in elite footballers, using the extent of the prognostic evidence and clinical reasoning; 2) explore potential PHE-derived PFs associated with IMI outcomes in elite footballers, using available PHE data from a professional team.

METHODS A retrospective review has been completed of PHE and injury data, routinely collected over 5 years (from 1st July 2013 to 19th May 2018) from a population of elite male players at an English Premier League football club. Of 60 candidate PFs, 15 were excluded. Ten factors will be included in model development, identified from a systematic review, missing data assessment, measurement reliability evaluation and clinical reasoning. A full multivariable logistic regression model will be fitted, to ensure adjustment before backward elimination. The performance and internal validation of the model will be assessed. The remaining 35 candidate PFs are eligible for further exploration, using univariable logistic regression to obtain unadjusted risk estimates. Exploratory PFs will be grouped according to type and incorporated into multivariable logistic regression models to determine risk estimates.

DISCUSSION This study will offer insights into clinical usefulness of a model to predict IMI risk in elite football and highlight the practicalities of model development in this setting. Exploration may identify other relevant PFs for future confirmatory studies, model updating, or influence future injury prevention research. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03782389
Study type Observational
Source Manchester United Football Club
Contact
Status Completed
Phase
Start date July 1, 2013
Completion date May 19, 2018
View Details
See also
  Status Clinical Trial Phase
Completed NCT05988476 - Investıgatıon of The Effıciency of Pulsed Electromagnetıc Field Therapy and Stretching Exercises N/A
Active, not recruiting NCT05344183 - Immediate and Short-term Effects of Low-level Laser N/A
Completed NCT05367648 - Effects of Protein Hydrolysate Supplement on Systemic Muscle Function Markers Following Resistance Type Exercise in Male Subjects N/A
Not yet recruiting NCT05279196 - Biological Variables Associated With the Response to Intensive Training in Athletes N/A
Completed NCT05254470 - Real-World Experience of Patients Treated for Musculoskeletal Injuries With SAM in Routine Care
Completed NCT03676205 - Platelet-Rich Plasma in Acute Muscle Injuries Phase 2
Completed NCT05827484 - The Effect of Combined Use of Anti-fibrotic Agent With Platelet Rich Plasma on Skeletal Muscle Healing After Acute Injuries Phase 4
Completed NCT04177537 - Real-World Experience of Athletes Treated With SAM
Completed NCT01525667 - Safety and Efficacy of IM Injections of PLX-PAD for the Regeneration of Injured Gluteal Musculature After Total Hip Arthroplasty Phase 1/Phase 2
Completed NCT04535635 - Effects of ART® on Lower Limb Myofascial Pain and Function N/A
Completed NCT04874662 - Nicotinamide (NAM) and Pyridoxine (Vitamin B6) on Muscle Regeneration ("Satellite-01 Study"). N/A
Completed NCT04742244 - Lemon Verbena Extract Oxidative Stress and Muscle Damage N/A
Active, not recruiting NCT04483986 - Does Rectus Re-approximation Cause Adhesion After Cesarean Section? N/A
Recruiting NCT05216666 - The Role of Surgical Approach on Residual Limping After Total Hip Arthroplasty N/A
Completed NCT02077413 - Muscle Injury Prevention & Rehabilitation in Military Personnel N/A
Withdrawn NCT01497678 - Musculotendinous Tissue Unit Repair and Reinforcement (MTURR) Coordinating Center N/A
Terminated NCT01751503 - Extramembranous and Interosseous Technique of Tibialis Posterior Tendon Transfer N/A
Completed NCT04586712 - Efficacy of a Controlled Short-term Trial of Cannabidiol (CBD) Ingestion on Reducing Symptomatic Response and Facilitating Recovery After Induced Muscle Injury Phase 2
Completed NCT04123782 - Focused Shockwave Treatment in the Recovery Process of Acute Muscle Injuries in Soccer Players N/A
Not yet recruiting NCT01097798 - To Evaluate the Efficacy and Safety Aliviador Compared to Gelol in Patients With Contusions, Sprains, Trauma and Muscle Injury. Phase 3