Clinical Trials Logo

Clinical Trial Details — Status: Active, not recruiting

Administrative data

NCT number NCT05663541
Other study ID # E-60116787-020-238650
Secondary ID
Status Active, not recruiting
Phase
First received
Last updated
Start date October 24, 2022
Est. completion date July 2024

Study information

Verified date November 2023
Source Pamukkale University
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Sensory disorders are one of the most important problems in individuals with MS, and these disorders are among the first symptoms of MS. Loss of sense of proprioception is particularly common in patients with MS. Studies show that assessment methods for the quantitative measurement of sensory disorders are lacking. Especially in the clinic, there is no evaluation method that evaluates the sense of proprioception. Therefore, the aim of this study perform the validity and reliability study of the lower extremity position test to evaluate proprioception sense in individuals with MS.


Recruitment information / eligibility

Status Active, not recruiting
Enrollment 90
Est. completion date July 2024
Est. primary completion date June 2024
Accepts healthy volunteers No
Gender All
Age group 20 Years to 65 Years
Eligibility Inclusion Criteria: - 20-65 years old - EDSS score between 0-5 - Person who has not had an attack in the last 1 month or who is not in the attack period - Person without systemic disease such as hypertension, heart disease, Diabetes Mellitus, hyperlipidemia, malignancy - Person who has not undergone surgery that restricts balance function in the lower extremity. - Person without hip, knee and ankle contracture - Person who does not have additional neurological disease - Person who does not use vestibulosupressants or drugs that may cause neuropathy and does not have a history of alcohol use - To have full cooperation and adaptation to the work - Individuals who agree to receive treatment will be included in the study. Exclusion Criteria: - Being younger than 20 years old and over 65 years old - Being in the attack period - Hip, knee or ankle contracture - Being greater than EDSS 5 - Having systemic diseases such as hypertension, heart disease, Diabetes Mellitus, hyperlipidemia, malignancy - Having an additional neurological disease - Having a vestibulospressant or drug or alcohol use habit that causes neuropathy - Not cooperating and adapting to the work

Study Design


Intervention

Diagnostic Test:
Lower extremity position test
Assessing proprioception of the lower extremity of individuals multiple sclerosis

Locations

Country Name City State
Turkey Romatem Bursa Fizik Tedavi ve Rehabilitasyon Hastanesi Bursa

Sponsors (1)

Lead Sponsor Collaborator
Pamukkale University

Country where clinical trial is conducted

Turkey, 

Outcome

Type Measure Description Time frame Safety issue
Primary Sensorial Assessment-1 Lower Extremity Position test through study completion, an average of 1 year
Primary Sensorial Assessment-2 Kinesthesia (Inclinometer) through study completion, an average of 1 year
Primary Balance Assessment-1 Static Balance via single leg stance through study completion, an average of 1 year
Primary Balance Assessment-2 Dynamic Balance via time up and go through study completion, an average of 1 year
Primary Walking Speed Assessment The 10 meter walk test through study completion, an average of 1 year
Secondary Demographic Assessment Demographic form through study completion, an average of 1 year
Secondary Expanded Disability Status Scale (EDSS) Ranges from 0 to 10 in 0.5 unit increments that represent higher levels of disability. through study completion, an average of 1 year
See also
  Status Clinical Trial Phase
Completed NCT05528666 - Risk Perception in Multiple Sclerosis
Completed NCT03608527 - Adaptive Plasticity Following Rehabilitation in Multiple Sclerosis N/A
Recruiting NCT05532943 - Evaluate the Safety and Efficacy of Allogeneic Umbilical Cord Mesenchymal Stem Cells in Patients With Multiple Sclerosis Phase 1/Phase 2
Completed NCT02486640 - Evaluation of Potential Predictors of Adherence by Investigating a Representative Cohort of Multiple Sclerosis (MS) Patients in Germany Treated With Betaferon
Completed NCT01324232 - Safety and Efficacy of AVP-923 in the Treatment of Central Neuropathic Pain in Multiple Sclerosis Phase 2
Completed NCT04546698 - 5-HT7 Receptor Implication in Inflammatory Mechanisms in Multiple Sclerosis
Active, not recruiting NCT04380220 - Coagulation/Complement Activation and Cerebral Hypoperfusion in Relapsing-remitting Multiple Sclerosis
Completed NCT02835677 - Integrating Caregiver Support Into MS Care N/A
Completed NCT03686826 - Feasibility and Reliability of Multimodal Evoked Potentials
Recruiting NCT05964829 - Impact of the Cionic Neural Sleeve on Mobility in Multiple Sclerosis N/A
Withdrawn NCT06021561 - Orofacial Pain in Multiple Sclerosis
Completed NCT03653585 - Cortical Lesions in Patients With Multiple Sclerosis
Recruiting NCT04798651 - Pathogenicity of B and CD4 T Cell Subsets in Multiple Sclerosis N/A
Active, not recruiting NCT05054140 - Study to Evaluate Efficacy, Safety, and Tolerability of IMU-838 in Patients With Progressive Multiple Sclerosis Phase 2
Completed NCT05447143 - Effect of Home Exercise Program on Various Parameters in Patients With Multiple Sclerosis N/A
Recruiting NCT06195644 - Effect of Galvanic Vestibular Stimulation on Cortical Excitability and Hand Dexterity in Multiple Sclerosis Patients Phase 1
Completed NCT04147052 - iSLEEPms: An Internet-Delivered Intervention for Sleep Disturbance in Multiple Sclerosis N/A
Completed NCT03594357 - Cognitive Functions in Patients With Multiple Sclerosis
Completed NCT03591809 - Combined Exercise Training in Patients With Multiple Sclerosis N/A
Completed NCT02845635 - MS Mosaic: A Longitudinal Research Study on Multiple Sclerosis