Multiple Sclerosis Clinical Trial
Official title:
Large-scale, Multi-disciplinary Sample and Data Repository for Multiple Sclerosis and Related Demyelinating Diseases
| NCT number | NCT00445367 |
| Other study ID # | ACP-001 |
| Secondary ID | |
| Status | Active, not recruiting |
| Phase | |
| First received | |
| Last updated | |
| Start date | May 2006 |
| Est. completion date | October 2036 |
| Verified date | April 2024 |
| Source | Accelerated Cure Project for Multiple Sclerosis |
| Contact | n/a |
| Is FDA regulated | No |
| Health authority | |
| Study type | Observational |
To establish a large, longitudinal collection of high quality samples and data from subjects with MS, selected other demyelinating diseases (Transverse Myelitis (TM), Neuromyelitis Optica (NMO) or Devic's, Acute Disseminated Encephalomyelitis (ADEM), and Optic Neuritis (ON)), and related and unrelated unaffected controls. Samples and data will be available as a shared resource to scientists researching the causes, sub-types, and biomarkers of MS and related demyelinating diseases.
| Status | Active, not recruiting |
| Enrollment | 3226 |
| Est. completion date | October 2036 |
| Est. primary completion date | October 2026 |
| Accepts healthy volunteers | Accepts Healthy Volunteers |
| Gender | All |
| Age group | N/A and older |
| Eligibility | Inclusion Criteria: - age 18+ able to give informed consent or individuals younger than 18 with parental permission and able to give assent - willing to provide up to 110 ml (50 ml for < 18 years old) of blood via venipuncture - experienced at least one CNS demyelinating event characteristic of MS, TM, NMO, ADEM, or ON Exclusion Criteria: - history of blood borne pathogens - allogeneic bone marrow transplant - clinical or radiological evidence of stroke, meningitis, or other well characterized diseases of the nervous system (with the exception of MS, TM, NMO, ADEM, or ON). - weight less than 37 pounds |
| Country | Name | City | State |
|---|---|---|---|
| United States | Shepherd Center | Atlanta | Georgia |
| United States | The Rocky Mountain MS Center at Anschutz Medical Campus at UC Denver | Aurora | Colorado |
| United States | Johns Hopkins | Baltimore | Maryland |
| United States | Beth Israel Deaconess | Boston | Massachusetts |
| United States | The Ohio State University | Columbus | Ohio |
| United States | University of Texas Southwestern Medical Center at Dallas | Dallas | Texas |
| United States | Multiple Sclerosis Research Center of New York | New York | New York |
| United States | Barrow Neurological Institute | Phoenix | Arizona |
| United States | Stanford University | Stanford | California |
| United States | University of Massachusetts Medical School | Worcester | Massachusetts |
| Lead Sponsor | Collaborator |
|---|---|
| Accelerated Cure Project for Multiple Sclerosis |
United States,
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