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Clinical Trial Summary

To assess the safety, immunogenicity and preliminary efficacy of 3D189 in patients with hematological malignancies.


Clinical Trial Description

This is a phase 1, open-label, non-comparative, multicenter study of 3D189 (also known as galinpepimut-S), a multivalent peptide vaccine targeting Wilms Tumor-1 (WT1), for maintenance immunotherapy in patients with WT1-positive hematological malignancies, including patients with acute leukemia (AL) patients in complete remission (CR), or multiple myeloma (MM), non-Hodgkin lymphoma (NHL) or higher-risk myelodysplastic syndrome (MDS) patients who have received at least first-line standard therapy and recently achieved CR or partial remission (PR), if the latter is the best achievable response for the patient. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05320809
Study type Interventional
Source 3D Medicines
Contact
Status Active, not recruiting
Phase Phase 1
Start date August 1, 2022
Completion date December 2024

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