Multiple Myeloma Clinical Trial
— MYRACLEOfficial title:
MYeloma Resistance And Clonal Evolution
Multiple Myeloma (MM) is often associated with progression, temporary response to therapy and a high relapse rate over time resulting in a poor long-term prognosis. Because MM is classified as an incurable disease, therapeutic resistance is of great interest. However, knowledge about the biological mechanisms underlying resistance associated with MM therapies and about associated predictors remains poor. The MYRACLE cohort, a multicenter prospective cohort of patients with MM, is set up to address this limitation.
Status | Recruiting |
Enrollment | 1400 |
Est. completion date | February 11, 2029 |
Est. primary completion date | February 11, 2029 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility | Inclusion Criteria: - Patient with diagnosis of multiple myeloma according to standard criteria - Age >18 Exclusion Criteria: - Minor patient - Patient under guardianship - Protected patient |
Country | Name | City | State |
---|---|---|---|
France | La Roche sur Yon Hospital Departmental | La Roche-sur-Yon | |
France | Nantes University Hospital | Nantes |
Lead Sponsor | Collaborator |
---|---|
Nantes University Hospital |
France,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Describe the mechanisms of resistance of myeloma cells. | Number of resistance. | Ten years |
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