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NCT05274685 Clinical Trial

Early Renal Replacement Therapy in COVID 19 Patients With AKI Does it Improve the Outcome?

Multi Organ Failure Clinical Trial

Official title:
Early Renal Replacement Therapy in COVID 19 Patients With AKI Improves the Prognosis of the Disease

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT05274685
Other study ID # soh-Med-22-2-24
Secondary ID
Status Completed
Phase N/A
First received
Last updated
Start date June 1, 2021
Est. completion date January 1, 2022

Study information
Verified date February 2022
Source Sohag University
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

patients will be divided into two equal groups, each group including 50 adult patients with a confirmed diagnosis of covid, patients with acute kidney injury, the first group will be treated with early hemodialysis, second group will be conservative until there is an urgent need for dialysis

Recruitment information / eligibility
Status Completed
Enrollment 100
Est. completion date January 1, 2022
Est. primary completion date December 1, 2021
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: - adult patients (=18 years old) with confirmed severe acute respiratory syndrome coronavirus 2 infections admitted to the ICU. Exclusion Criteria: - •Malignancy. - Immuno-deficiency diseases. - Chronic diabetic, cardiac and hypertensive patients - autoimmune diseases.

Study Design

Related Conditions & MeSH terms

Intervention

Procedure:
• haemodialysis
continuous venovenous hemodiafiltration (CVVHDF) at a prescribed dose of 30-35 mL/kg/h of effluent and with regional citrate anticoagulation

Locations
Country Name City State
Egypt Faculty of Medicine, Sohag University Sohag

Sponsors (1)
Lead Sponsor Collaborator
Sohag University

Country where clinical trial is conducted

Egypt, 

Outcome
Type Measure Description Time frame Safety issue
Primary reduction of Sequential Organ Failure Assessment Score prevention of multi-organ failure associated with covid including respiratorym circulatory, liver and renal failure 2 weeks
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